ID F7CQK0_XENTR Unreviewed; 386 AA.
AC F7CQK0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};
GN Name=b3gnt3.2 {ECO:0000313|Ensembl:ENSXETP00000035853,
GN ECO:0000313|RefSeq:XP_012809211.1, ECO:0000313|RefSeq:XP_012809212.1,
GN ECO:0000313|Xenbase:XB-GENE-996589};
GN Synonyms=b3gnt3 {ECO:0000313|RefSeq:XP_012809211.1,
GN ECO:0000313|RefSeq:XP_012809212.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000035853};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000035853}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000035853};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000035853}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_012809211.1, ECO:0000313|RefSeq:XP_012809212.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_012809211.1,
RC ECO:0000313|RefSeq:XP_012809212.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_012809211.1,
RC ECO:0000313|RefSeq:XP_012809212.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU363063}; Single-pass type II membrane protein
CC {ECO:0000256|RuleBase:RU363063}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661, ECO:0000256|RuleBase:RU363063}.
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DR RefSeq; XP_012809211.1; XM_012953757.3.
DR RefSeq; XP_012809212.1; XM_012953758.3.
DR Ensembl; ENSXETT00000035853; ENSXETP00000035853; ENSXETG00000016436.
DR Ensembl; ENSXETT00000105603; ENSXETP00000108178; ENSXETG00000016436.
DR GeneID; 100145701; -.
DR AGR; Xenbase:XB-GENE-996589; -.
DR CTD; 100002020; -.
DR Xenbase; XB-GENE-996589; b3gnt3.2.
DR eggNOG; KOG2287; Eukaryota.
DR HOGENOM; CLU_036849_5_3_1; -.
DR OMA; VSYLQGH; -.
DR OrthoDB; 532757at2759; -.
DR TreeFam; TF318639; -.
DR Reactome; R-XTR-2022854; Keratan sulfate biosynthesis.
DR Reactome; R-XTR-913709; O-linked glycosylation of mucins.
DR Proteomes; UP000008143; Chromosome 1.
DR Bgee; ENSXETG00000016436; Expressed in egg cell and 9 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11214:SF23; N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363063};
KW Golgi apparatus {ECO:0000256|RuleBase:RU363063};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ SEQUENCE 386 AA; 43647 MW; 856A2B28BED5B180 CRC64;
MRRKFFKTEI FVLLAVGIPS LLFILWEDQN NQLVLEEIEE PSPERLADNN TIDSPAVKIE
WKSSCKANYS VENISGFSDL PPHIKDFLIY RHCRSFPIII DAPSKCGGPS ASKGVFLLLA
IKSSPGNYER RAVIRQTWGA EETYGTAKVR RIFISGISKA NMEVKRMNKL LKIESQKFGD
ILQWDFQDTF FNLTLKQLLF HQWLDENCPG ANFIFNGDDD VFVNTFNVIA FSQGLGEHGA
DKHLYVGQLI ANVGPIRESQ SKYYVPVQVT TSDSYPRYCG GGGILMSRFT CLSISNQSKS
IELFPIDDVY LGMCLEKAGL VPASHMGMRT VGVKVPSDTL DSFDPCYYRE LLMVHRFVPY
EMIVMWNAIQ DSKLDCGQKH AIYIGV
//
