ID   F7CT31_CALJA            Unreviewed;       550 AA.
AC   F7CT31;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 4.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=Rho GTPase activating protein 9 {ECO:0000313|Ensembl:ENSCJAP00000013616.5};
GN   Name=ARHGAP9 {ECO:0000313|Ensembl:ENSCJAP00000013616.5};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000013616.5, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000013616.5}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000013616.5}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_009002347.1; XM_009004099.2.
DR   AlphaFoldDB; F7CT31; -.
DR   STRING; 9483.ENSCJAP00000013616; -.
DR   Ensembl; ENSCJAT00000014341.5; ENSCJAP00000013616.5; ENSCJAG00000007264.5.
DR   GeneTree; ENSGT00950000182860; -.
DR   HOGENOM; CLU_015883_6_1_1; -.
DR   InParanoid; F7CT31; -.
DR   Proteomes; UP000008225; Chromosome 9.
DR   Bgee; ENSCJAG00000007264; Expressed in kidney and 6 other cell types or tissues.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd13233; PH_ARHGAP9-like; 1.
DR   CDD; cd04403; RhoGAP_ARHGAP27_15_12_9; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR23176:SF103; RHO GTPASE-ACTIVATING PROTEIN 9; 1.
DR   PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT   DOMAIN          35..63
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          138..251
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          342..549
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          59..108
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..314
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   550 AA;  61361 MW;  643D641F9E0A994D CRC64;
     MSEPPVYCNL VDLRCCPRSP LPGPACPLLQ RLDAWEQHLD PNSGRCFYIN SLTGCKSWKP
     PRCSRGQTNP GSMEGTQTRK RDNDVLQPQA KGLGSDTGTP EPIDPQGSLS LSQRTLQLDP
     PALQPSRPVP QLLDDPREVE KSGLLNMTKI AQGGRKLRKN WGPSWVVLAG NSLVFYREPP
     PTAPSSGWGP PGSRPESSVD LRGAALAHGR HLSSRRNVLH IRTVPGHEFL LQSDQETELR
     AWHRALRAVI ERLDRENPLE LRLSGSGPAE LAELSAGEDE EEESEQVSKP LLRLSGRRSS
     SRRPEGAEQN RVRNKLKRLI AKRPPLQSLQ ERGLLRDQVF GCQLESLCQR EGDTVPSFVR
     LCIAAVDKRG LDVDGIYRVS GNLAVVQKLR FLVDRERTVT SDGRYLFPEQ PGQEGRLDLD
     SAEWDDIHVV TGALKLFLRE LPQPLVPQLL LPHFRAALAL LESEQCLSQI QELIGSMPKP
     NHDTLRYLLE HLCRVIAHSD KNRMTPHNLG IVFGPTLFRP EQETSDPAAH ALYPGQLVQL
     MLTNFTSLFP
//