ID   F7CUY9_ORNAN            Unreviewed;       398 AA.
AC   F7CUY9;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   02-DEC-2020, sequence version 2.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Selenoprotein I {ECO:0000313|Ensembl:ENSOANP00000000835.2};
GN   Name=SELENOI {ECO:0000313|Ensembl:ENSOANP00000000835.2};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000000835.2, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000000835.2}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000000835.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC   -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC       family. {ECO:0000256|ARBA:ARBA00010441, ECO:0000256|RuleBase:RU003750}.
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DR   AlphaFoldDB; F7CUY9; -.
DR   STRING; 9258.ENSOANP00000000835; -.
DR   Ensembl; ENSOANT00000000836.2; ENSOANP00000000835.2; ENSOANG00000000523.2.
DR   eggNOG; KOG2877; Eukaryota.
DR   GeneTree; ENSGT00950000183117; -.
DR   HOGENOM; CLU_035066_2_0_1; -.
DR   InParanoid; F7CUY9; -.
DR   OMA; QNMGQGW; -.
DR   TreeFam; TF313270; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000000523; Expressed in liver and 7 other cell types or tissues.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0004307; F:ethanolaminephosphotransferase activity; IBA:GO_Central.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IBA:GO_Central.
DR   Gene3D; 1.20.120.1760; -; 1.
DR   InterPro; IPR000462; CDP-OH_P_trans.
DR   InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR   InterPro; IPR048254; CDP_ALCOHOL_P_TRANSF_CS.
DR   InterPro; IPR014472; CHOPT.
DR   PANTHER; PTHR10414; ETHANOLAMINEPHOSPHOTRANSFERASE; 1.
DR   PANTHER; PTHR10414:SF47; ETHANOLAMINEPHOSPHOTRANSFERASE 1; 1.
DR   Pfam; PF01066; CDP-OH_P_transf; 1.
DR   PIRSF; PIRSF015665; CHOPT; 1.
DR   PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE   3: Inferred from homology;
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023209};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW   Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003750};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        48..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        222..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        256..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        346..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   398 AA;  45437 MW;  6908744A86D6A133 CRC64;
     MALGYEYVSA EQLAGFDKYK YSALDTNPLS LYVMHPFWNT IVKIFPTWLA PNLITFSGFL
     LLVFNFLLMA YFDPDFYASA PGQKHVPDWV WIVVGILNFT AYTLDGVDGK QARRTNSSTP
     LGELFDHGLD SWACVYFVVT VYSIFGRGRT GVSVFVLYLL LWVVLFSFIL SHWEKYNTGI
     LFLPWGYDMS QVTISIVYIV TAVVGVEAWY EPFLFNFLYR DLFTTMIIGC AVTVTLPMSL
     YNFCKAYRNK TLKYSSVYET MLPFVSPCLL FTLSTTWIFL SPSNILETHP RLFYFMVGTL
     FANITCQLIV CQMSNTRCQP LNWLLMPLAL VILVVHSGLA PHSETFLLYS LTALVTVAHI
     HYGIRVVNQL SKHFKILPFS LRKPSSDLGL EEEKIGLQ
//