ID F7DBB6_CALJA Unreviewed; 669 AA.
AC F7DBB6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Rhophilin Rho GTPase binding protein 1 {ECO:0000313|Ensembl:ENSCJAP00000039915.4};
GN Name=RHPN1 {ECO:0000313|Ensembl:ENSCJAP00000039915.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000039915.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000039915.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000039915.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RHPN family.
CC {ECO:0000256|ARBA:ARBA00010369}.
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DR AlphaFoldDB; F7DBB6; -.
DR Ensembl; ENSCJAT00000042169.4; ENSCJAP00000039915.4; ENSCJAG00000021444.6.
DR eggNOG; KOG2220; Eukaryota.
DR GeneTree; ENSGT00940000153837; -.
DR HOGENOM; CLU_006514_3_0_1; -.
DR TreeFam; TF323502; -.
DR Proteomes; UP000008225; Chromosome 16.
DR Bgee; ENSCJAG00000021444; Expressed in kidney and 6 other cell types or tissues.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.280; alix/aip1 like domains; 1.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR004328; BRO1_dom.
DR InterPro; IPR038499; BRO1_sf.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR047138; RHPN1_2.
DR PANTHER; PTHR23031; RHOPHILIN; 1.
DR PANTHER; PTHR23031:SF6; RHOPHILIN-1; 1.
DR Pfam; PF03097; BRO1; 1.
DR Pfam; PF02185; HR1; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM01041; BRO1; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51180; BRO1; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 23..97
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 108..457
FT /note="BRO1"
FT /evidence="ECO:0000259|PROSITE:PS51180"
FT DOMAIN 513..580
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 669 AA; 73235 MW; 9BC39F2F05432E4C CRC64;
MILEERPDGA GTGEKSARLQ GCDSLTQTQR GQLQSRRARI YQQINKELQM RTGAENLYRA
TSNSRVRETV ALELSYVNSH LQLLKEELEE LSGGTDSGRH GSEAVTVPMI PLGLKETKEL
DWSTPLKELI SVHFGEDGTS YEAEIRELEA LRQAMRTPSR NEAGLELLTT YYHQLCLLDA
RFLTPARSLG LFFQWYDSLT GVPAQQRALA FEKGSVLFNI GALHTQIGAR QDRTCIEGAH
CAVEAFQRAA GAFSLLRENF SNAPSPDMSA VSLCALEQLM MAQAQECVFE GLSPPASMAP
RNCLAQLHLA QEAAQVAAEY RLVHRTMAQP PVHDYVPVSW TTLVHVKAEY FCSLAHYHIA
MALCDGSPAT EGELPAHEQV FLQPPTFSNP RGPALPLELE ERRKLGKAHL KRAILGQEEA
LRLHMLCRVL REVDLLRAVV AQALQCSLAK YSELDCEDDF CEAAEAPDIR PKTRQKPEAR
MPCLSQGKGP DIFHRLGPLS VFSAKNRWRL VGPIHLTRGE GGFGLTLRGD SPVLIAAVIP
GGQAAAAGLK EGDYIVAVNG QPCRWWRHAE VVAELRAAGD AGASLQVVSL LPSSGLPGLG
DRRPTLLGPR GFLRSQREHG CQTPACTRAS PRPLLGWSRK TQQGKTGGRL QPCAPAKALS
TCCCPGHRP
//
