ID F7DP10_XENTR Unreviewed; 525 AA.
AC F7DP10; A0A1B8Y252;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=DEP domain containing 1B {ECO:0000313|Ensembl:ENSXETP00000013376};
GN Name=depdc1b {ECO:0000313|Ensembl:ENSXETP00000013376};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000013376};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000013376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000013376};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000013376}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
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DR AlphaFoldDB; F7DP10; -.
DR Ensembl; ENSXETT00000013376; ENSXETP00000013376; ENSXETG00000006073.
DR AGR; Xenbase:XB-GENE-991208; -.
DR Xenbase; XB-GENE-991208; depdc1b.
DR eggNOG; ENOG502QR00; Eukaryota.
DR HOGENOM; CLU_040757_0_0_1; -.
DR OrthoDB; 2902712at2759; -.
DR TreeFam; TF328365; -.
DR Bgee; ENSXETG00000006073; Expressed in blastula and 9 other cell types or tissues.
DR ExpressionAtlas; F7DP10; baseline and differential.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04405; RhoGAP_BRCC3-like; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR16206; DEP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR16206:SF11; DEP DOMAIN-CONTAINING PROTEIN 1B; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00049; DEP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
FT DOMAIN 194..389
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 525 AA; 61695 MW; 4658951772A6D55F CRC64;
MLTYPQCCTI IHYTYRITYK ATNNLYKRHR VHFKIHDRCF SATEAVDFLH ELLQCNQNFG
PEVTRTQTIQ LLKKFQKNHV IEDVKGRWGK EDFEDNGCLY RFPPTSPLKP YPKRPPCRVE
PIPFPQWSDQ GSLTSRVQIH GKSIDMNSEA WYKRHSIAIG EVPMCRLVKR RELTAAHVEE
IWKSRTLLQL KKILGLDSLN DVMDTKWVEA KHILHNIHNT NKQGIVVLDD RSKELPHWLL
SAMKCLANWP NCSDWNQPMY LGFERDVFRT ITDYHSFLKE PLLTFHLFDV FVNALGLLQK
KRVAIEALQL CCLLLPPENR RKLQLLMRMM AKISLNREMP PLRDSTGNRA LMVQTFSRCI
LRSKDEVDLD ELLSTKLVTF MMDNAPDILT VPITLKNNIE DYVAHQRRVQ IKYPGSDMET
TLNPTFVQPQ APAHDYEYQK LSRPEDPAKI LLEEILSNKQ ISAKEKKKRL KQFQRCHPEI
YKQRFPTPDS EAALFPERPS LKSQLSFFTL KRPFQSFQRT RSFRM
//
