ID F7EGI9_CALJA Unreviewed; 1188 AA.
AC F7EGI9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 4.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Sorbin and SH3 domain containing 2 {ECO:0000313|Ensembl:ENSCJAP00000047548.4};
GN Name=SORBS2 {ECO:0000313|Ensembl:ENSCJAP00000047548.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000047548.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000047548.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000047548.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSCJAT00000054443.4; ENSCJAP00000047548.4; ENSCJAG00000006015.5.
DR GeneTree; ENSGT00940000157056; -.
DR Proteomes; UP000008225; Chromosome 3.
DR Bgee; ENSCJAG00000006015; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd11920; SH3_Sorbs2_1; 1.
DR CDD; cd11923; SH3_Sorbs2_2; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 3.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1161..1187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 165..229
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 946..1005
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1021..1082
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1124..1188
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 25..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 901..948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1085..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..266
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..933
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1188 AA; 132490 MW; 0A1B055ECE8C4FFD CRC64;
MNTDSGGSAR KRAAMSVTLT SVKRVQSSPN LLAAGRDSQS PDSAWRSYHG NQEALNGDAT
YSSLAAKGFR SVRPNLQDKR SPTQSQITVN GNSGGAVSPM SYYQRPFSPS AYSLPASLNS
SIVMQHGTSL DSAETYPQHA QSLDGTSSSS IPLYRSSEEE KRVTVIKAPH YPGIGPVDES
GIPTAIRTTV DRPKDWYKTM FKQIHMVHKP GLYNPPYSAQ SHPAAKTQTY RPLSKSHSDN
STHAFKDASS PVPPPHVPPP VPPLRPRDRS STEKHDWDPP DRKVDTRKFR SEPRSIFEYE
PGKSSILQHE RPASLYQSSI DRSLERPMSS ASSASDFRKR RKSEPAVGPP RGLGDQRTSP
GRADLPGSST TLTKSFTSSS PSSPSRAKGG DDSKMCPSLC SYSGLDGNPP SELDYCSTYR
QLLDVPRDSP RAITFKNGWQ MARQNAEIWS STEETVSPKI KSRSCDDLLN DDCDSFPDPK
IKSESMGSLL CDKDSKGSCA ITWGSPYIQE VRSNGRSRIR HRSAHNAPGF LKMYKKMHRI
NRKDLMNSEV ICSVKSRILQ YENEQQPKGL GHAWSQSSTE EVPRDMVPTR ISEFEKLIQK
SKSMPNLGDD ALSPVTLEPP RNGLCPKRRF SIEYLLEDED EGGRPAPAPR GCASNALVPI
HIEVTSHEQP RAHVEFSDSD QDGVVSDHSD YIHVEGSSFC SESDLDHFSF TSSESFYGSS
HHHHHHHHHH HHHRHLISSC KGRCPASYTR FTTMLKHERA RHENTEEPRR PEMDPGLSKL
AFLVSPVPFR RKRNSAPKKQ TEKAKCKASV FEALDSALKD ICDQIKAEKK RGSLPDNSIL
HRLISELLPD VPERNSSLSV LRRSPLHLPL HPLPPDGAIH CPPYQNDGGR TPLSASFQDV
DTASNSYHPQ DRGGTLQDRE SPRSYSSTLT DMGRSGPRER RGTPEKEKLP AKAVYDFKAQ
TSKELSFKKG DTVYILRKID QNWYEGEHHG RVGIFPISYV EKLTPPEKAQ PARPPPPAQP
GEIGEAIAKY NFSADTNVEL SLRKGDRVIL LKRVDQNWYE GKIPGANRQG IFPVSYVEVV
KKNTKGAEDY PDPPMPHSYS SDRIHSLSSN KPQRPVFTHE NIQGGGEPFQ ALYNYTPRNE
DELELRESDV IDVMEKCDDG WFVGMCAFSS ETFGYFVLCL SFLTCVVR
//
