ID   F7F597_CALJA            Unreviewed;       560 AA.
AC   F7F597;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=UDP glycosyltransferase 8 {ECO:0000313|Ensembl:ENSCJAP00000006301.3};
GN   Name=UGT8 {ECO:0000313|Ensembl:ENSCJAP00000006301.3};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000006301.3, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000006301.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000006301.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}.
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DR   RefSeq; XP_008991026.1; XM_008992778.2.
DR   AlphaFoldDB; F7F597; -.
DR   STRING; 9483.ENSCJAP00000006301; -.
DR   Ensembl; ENSCJAT00000006649.5; ENSCJAP00000006301.3; ENSCJAG00000003461.5.
DR   GeneID; 100396627; -.
DR   CTD; 7368; -.
DR   eggNOG; KOG1192; Eukaryota.
DR   GeneTree; ENSGT00940000156545; -.
DR   HOGENOM; CLU_012949_3_1_1; -.
DR   InParanoid; F7F597; -.
DR   OMA; TKNCDMI; -.
DR   OrthoDB; 382054at2759; -.
DR   TreeFam; TF315472; -.
DR   Proteomes; UP000008225; Chromosome 3.
DR   Bgee; ENSCJAG00000003461; Expressed in cerebellum and 3 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0030913; P:paranodal junction assembly; IEA:Ensembl.
DR   GO; GO:0002175; P:protein localization to paranode region of axon; IEA:Ensembl.
DR   CDD; cd03784; GT1_Gtf-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR002213; UDP_glucos_trans.
DR   InterPro; IPR035595; UDP_glycos_trans_CS.
DR   PANTHER; PTHR48043:SF161; 2-HYDROXYACYLSPHINGOSINE 1-BETA-GALACTOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR   Pfam; PF00201; UDPGT; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR   PROSITE; PS00375; UDPGT; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000256|RuleBase:RU003718};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        26..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        491..514
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   560 AA;  63709 MW;  C017E143666EAD91 CRC64;
     MQAVTAVICE KATLERHIAM KSYTPYFMLL WSAVGIAKAA KIIIVPPIMF ESHMYIFKTL
     ASALHERGHH TVFLLSEGRD ITPSNHYSLQ RYPGIFNSTT SDAFLQSKMR NIFSGRLTAI
     ELFDILDHYT KNCDMMVGNH ALIQDLKKEK FDLLLVDPND MCGFVIAHLL GVKYAVFSTG
     LWYPAEVGAP APLAYVPEFN SLLTDRMNLL QRMKNTGVYL ISRLGVSFLV LPKYERIMQK
     YNLLPEKSMY DLVHGSSLWM LCTDVALEFP RPTLPNVVYV GGILTKPASP LPEDLQRWVN
     GANEHGFVLV SFGAGVKYLS EDIANKLAGA LGRLPQKVIW RFSGPKPKNL GNNTKLIEWL
     PQNDLLGHSK IKAFLSHGGL NSIFETMYHG VPVVGIPLFG DHYDTMTRVQ AKGMGILLEW
     KTVTEKELYE ALVKVINNPS YRQRARKLSE IHKDQPGHPV NRTIYWIDYI IRHNGAHHLR
     AAVHQISFCQ YFLLDIAFVL LLGAALFYFL LSWVTKFIYR KIKSLWSRSR HSTVNGHYHN
     GILNGKYKRN GHIKHEKKVK
//