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Database: UniProt
Entry: F7FE64_ORNAN
LinkDB: F7FE64_ORNAN
Original site: F7FE64_ORNAN 
ID   F7FE64_ORNAN            Unreviewed;       965 AA.
AC   F7FE64;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   30-AUG-2017, entry version 47.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000014924};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000014924, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000014924, ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000014924,
RC   ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [2] {ECO:0000313|Ensembl:ENSOANP00000014924}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000014924};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOANP00000014924}.
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DR   STRING; 9258.ENSOANP00000014924; -.
DR   Ensembl; ENSOANT00000014927; ENSOANP00000014924; ENSOANG00000009384.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   GeneTree; ENSGT00830000128242; -.
DR   InParanoid; F7FE64; -.
DR   OMA; VINAIMM; -.
DR   OrthoDB; EOG091G00FK; -.
DR   TreeFam; TF339123; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000009384; -.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:GO_Central.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   GO; GO:0019228; P:neuronal action potential; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR008052; Na_channel_a4su_mammal.
DR   Pfam; PF00520; Ion_trans; 2.
DR   PRINTS; PR01665; NACHANNEL4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    257    277       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    367    384       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    404    431       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    861    889       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    944    964       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      140    437       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      758    965       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       28     53       {ECO:0000256|SAM:Coils}.
FT   COILED      435    466       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   965 AA;  109837 MW;  BD520570C3EB02B5 CRC64;
     PVPPGPSAPP VLVPPGPESL RPFTRESLAA IERRAEEEEA RRQRNKHLEV EEQERKPRGD
     LEAGRNLPLI YGDPPPETIG TPLEDLDPFY CDKKTFIVLN KGRAIFRFSA TPALYLLSPF
     SLIRRGAIRV LIHYGSLFDI LLSLILLTCP TQTVKLCPEG GRKTTYTFTG IYSFESLIKM
     LARGFCIDDF TFLRDPWNWL DFSVIMMAYL TEFVDMGNIS ALRTFRVLRA LKTITVIPGL
     KTIVGALIQS VKKLSDVMIL TVFCLSVFAL VGLQLFMGNL RQKCVRWPPP INETLQFYSP
     LWANGTGYDN GTGNYTFDWD SYISDEGNFY FLEGSNDALL CGNSSDAGHC PEGYLCMKAG
     RNPNYGYTSY DTFSWAFLAL FRLMTQDYWE NLFQLTLRAA GKTYMLFFVV IIFLGSFYLI
     NLILAVVAMA YAEQNDATLL EEQEKEKEYQ QLLAQLKKHQ EEQEKSPWIW PSESNQIHGS
     KGSSLGSSAV GKKLGAEATL ENGDGDPAQR KDCNGGLEQE IYRSWKQEKD QGFNRKWHRY
     YSCTIHMNIY IHVYGCPYSG CWELIGKVSR KRWDLRSTLK EFLGKGKDGL PQDSGGLRGH
     TAYTKNHDHT AHTKNHDHTV VTKDHDRTAH TKNLDHTAHI KDRNYTTLTK DHDHTTVTKD
     HDCTAHTKNL DHTVHTKDRN YTTQIKDHAT MLTQRTMTTQ RTIATQRTTA TLLIQKEHEH
     DHTANIKKHC SHRGPCPHYK HKETLLIQRT MTTHNVLFCL MLSNRFRPIA TSRAYLSQNT
     LLSINDLVFT GIFTAEMVLK LVALDPYEYF QQGWNVFDSI IVTLSLVELG LADVQGLSVL
     RSFRLMRVFK LAKSWPTLNM LIKIIGNSVG ALGNLTLVLA IIVFIFAVVG MQLFGKSYKE
     CVCKIAADCS LPRWHMHDFF HSFLIVFRIL CGEWIETMWD CMEVAGQAMC LTVFLMVMVI
     GNLVV
//
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