ID F7FZ39_CALJA Unreviewed; 495 AA.
AC F7FZ39; A0A2R8NF20;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Pleckstrin homology domain containing O2 {ECO:0000313|Ensembl:ENSCJAP00000066934.2};
DE SubName: Full=Pleckstrin homology domain-containing family O member 2 isoform 1 {ECO:0000313|EMBL:JAB13863.1};
GN Name=PLEKHO2 {ECO:0000313|EMBL:JAB13863.1,
GN ECO:0000313|Ensembl:ENSCJAP00000066934.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB13863.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000066934.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB13863.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB05790.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB51241.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB30291.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB13863.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB38386.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000066934.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMT01006071; JAB05790.1; -; mRNA.
DR EMBL; GAMS01009273; JAB13863.1; -; mRNA.
DR EMBL; GAMR01003641; JAB30291.1; -; mRNA.
DR EMBL; GAMQ01003465; JAB38386.1; -; mRNA.
DR EMBL; GAMP01001514; JAB51241.1; -; mRNA.
DR RefSeq; XP_002753276.1; XM_002753230.2.
DR STRING; 9483.ENSCJAP00000066934; -.
DR Ensembl; ENSCJAT00000067397.2; ENSCJAP00000066934.2; ENSCJAG00000040691.2.
DR GeneID; 100406371; -.
DR KEGG; cjc:100406371; -.
DR CTD; 80301; -.
DR eggNOG; ENOG502QVFF; Eukaryota.
DR GeneTree; ENSGT00530000063760; -.
DR HOGENOM; CLU_026551_3_0_1; -.
DR OrthoDB; 5313759at2759; -.
DR TreeFam; TF333115; -.
DR Proteomes; UP000008225; Chromosome 10.
DR Bgee; ENSCJAG00000040691; Expressed in ovary and 6 other cell types or tissues.
DR CDD; cd13317; PH_PLEKHO1_PLEKHO2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR043448; PKHO1/2.
DR PANTHER; PTHR15871; PH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15871:SF2; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY O MEMBER 2; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 18..119
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 181..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 54103 MW; EFF2022B170A3A2B CRC64;
MEEEGVKEVS EKPRGAQMVD KAGWIKKSSG GLLGFWKDRY LLLCQAQLLV YENEDEQKCV
ETVELGSYEK CQDLRALLKR KHRFILLRSP GNKVSDIKFQ APSGEEKESW IKALNEGINR
GKNKAFDEVK VDKSCALEHV TRDRVRGGQR RRPPTRIHLK EVASAASDGL LRLDLDVPDS
GPPVFAPSND VSEAQPREIP RALIPPTKPS LAPETTSLGD RADTDTLAGE RAPTPVSASS
EVSPESREDS ETPTGEDSGS EQRPNSVLPD KLKVSWENPS PQELPPAENA EPSQAPSSET
SEAAPREGGK PPTPPTPPPK ILSEKLKACM GEMKASGPPA PGTAQVSVNG MDDSPEPTKP
SQAEGTPGTP TKDATMSTAL PHWDLPPQFH PRCASLGDLL EEGPRRPLQP RERLYRAQLE
VKVASEQTEK LLNKVLGSEP APVSAETLLS QAVEQLRQAT QVLQEMRDLG ELSQETPGLR
EKRKELVTLY RRSAP
//
