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Database: UniProt
Entry: F7GBB2_CALJA
LinkDB: F7GBB2_CALJA
Original site: F7GBB2_CALJA 
ID   F7GBB2_CALJA            Unreviewed;       410 AA.
AC   F7GBB2;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   10-MAY-2017, entry version 17.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   Name=ATP6V0A4 {ECO:0000313|Ensembl:ENSCJAP00000023922};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000023922, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000023922, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000023922}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCJAP00000023922}.
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DR   EMBL; ACFV01054362; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01054363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01054364; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01054365; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01054366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01054367; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01054368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSCJAT00000025307; ENSCJAP00000023922; ENSCJAG00000012974.
DR   GeneTree; ENSGT00390000004941; -.
DR   Proteomes; UP000008225; Chromosome 8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM     60     84       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    104    123       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    202    223       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    229    253       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    260    279       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    299    318       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   410 AA;  46700 MW;  DA7640ED9C753C29 CRC64;
     ELSGSSMAPI MTTVQSKTAP PTFNRTNKFT AGFQNIVDAY GVGSYREINP APYTIITFPF
     LFAVMFGDCG HGTVMLLAAL WMVLNERHLL SQKTDNEIWN TFFHGRYLIL LMGIFSIYTG
     LIYNDCFSKS LNIFGSSWSV QPMFRNATWN THVMEENQYL QLDPAIPGVY SGNPYPFGID
     PIWNLASNKL TFLNSYKMKM SVVLGIVQMV FGVILSLFNH IYFRRTLNII LQFIPEMIFI
     LCLFGYLVFM IIFKWCCFDV YVSQHAPSIL IHFINMFLFN YSDSSNAPLY KYQQEVQSFF
     VVMALISVPW MLLIKPFILR ASLQKSQLQA SRIQEDGTEN IEGDSFSPSS SSGQRTSADA
     HGTQDNHEEE EFNFGDVFVH QAIHTIEYCL GCISNTASYL RLWALSLAHA
//
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