ID F7H451_CALJA Unreviewed; 514 AA.
AC F7H451;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Chromodomain helicase DNA binding protein 2 {ECO:0000313|Ensembl:ENSCJAP00000050183.1};
GN Name=CHD2 {ECO:0000313|Ensembl:ENSCJAP00000050183.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000050183.1, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000050183.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000050183.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
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DR AlphaFoldDB; F7H451; -.
DR Ensembl; ENSCJAT00000063721.3; ENSCJAP00000050183.1; ENSCJAG00000020444.5.
DR GeneTree; ENSGT00940000155888; -.
DR Proteomes; UP000008225; Chromosome 6.
DR Bgee; ENSCJAG00000020444; Expressed in cerebellum and 6 other cell types or tissues.
DR CDD; cd18666; CD1_tandem_CHD1-2_like; 1.
DR CDD; cd18661; CD2_tandem_CHD1-2_like; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR023779; Chromodomain_CS.
DR InterPro; IPR038718; SNF2-like_sf.
DR PANTHER; PTHR45623:SF19; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2; 1.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR Pfam; PF00385; Chromo; 2.
DR SMART; SM00298; CHROMO; 2.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR PROSITE; PS00598; CHROMO_1; 2.
DR PROSITE; PS50013; CHROMO_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 274..366
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 391..469
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 31..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..213
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..264
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 514 AA; 58471 MW; 3A1268AB3A6B62A0 CRC64;
MAHKQREDYL NLAPCILTWY RTLSQLAFDG EKLSHSASEE ASGSDSGSQS ESEQGSDPGS
GHGSESNSSS ESSESQSESE SESAGSKSQP VLPEAKEKPA SKKERIADVK KMWEEYPDVY
GVRRSNRSRQ EPSRFNIKEE ASSGSESGSP KRRGQRQLKK QEKWKREPSE DEQEQGTSAE
SEPEQKKVKA RRPVPRRTVP KPRVKKQPKT QRGKRKKQES SDEDDDDDEA PKRQTRRRAA
KNVSYKEDDD FETDSDDLIE MTGEGVDEQQ DNSETIEKVL DSRLGKKGAT GASTTVYAIE
ANGDPSGDFD TEKDDGEVQY LIKWKGWSYI HSTWESEESL QQQKVKGLKK LENFKKKEDE
IKQWLGKVSP EDVEYFNCQQ ELASELNKQY QIVERVIAVK TSKSTLGQTD FPAHSRKPAP
SNEPEYLCKW MGLPYSECSW EDEALIGKKF QNCIDGFHSR NNSKTIPTRE CKALKQRPRF
VALKKQPTYL GGENLELRDY QLEGLNWLAH SWCK
//
