ID F7HCR5_MACMU Unreviewed; 712 AA.
AC F7HCR5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=LRRC37A/B like protein 1 C-terminal domain-containing protein {ECO:0000259|Pfam:PF14914};
GN Name=LRRC37A {ECO:0000313|Ensembl:ENSMMUP00000024288.4};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000024288.4, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000024288.4}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000024288.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7HCR5; -.
DR Ensembl; ENSMMUT00000025957.4; ENSMMUP00000024288.4; ENSMMUG00000057840.1.
DR VEuPathDB; HostDB:ENSMMUG00000057840; -.
DR eggNOG; ENOG502QVVG; Eukaryota.
DR GeneTree; ENSGT00530000063282; -.
DR HOGENOM; CLU_015957_0_0_1; -.
DR TreeFam; TF341959; -.
DR Proteomes; UP000006718; Chromosome 16.
DR Bgee; ENSMMUG00000057840; Expressed in spermatid and 19 other cell types or tissues.
DR ExpressionAtlas; F7HCR5; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR015753; LRRC37.
DR InterPro; IPR029423; LRRC37AB_C.
DR PANTHER; PTHR23045; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A; 1.
DR PANTHER; PTHR23045:SF9; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A-RELATED; 1.
DR Pfam; PF14914; LRRC37AB_C; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 674..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 560..703
FT /note="LRRC37A/B like protein 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14914"
FT REGION 306..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 80142 MW; 5A95E586DA617117 CRC64;
MQFLHKLILN RNPLTAVEDP YLFELPALKY LDMGTTQVPL ATLKNILTMT VELEKLILPS
RMACCLCQFK NSIEAVCKTV KLHCNSACLT NTIHCPEELS VGNPEGAFMK VLQARKKHTS
TELTIEPEVP SDRSGINFSG FGSEQLDTND ENEVISALSY ILPYFSAGNL DAESILLPFT
KLLFANVQDR DRPLSILKNN TNSPSLQPAS NNSTYENKLR KLYLLEKILD AEKQEKINEV
KRDEKTAMLM QSSLLGNKFK RQLFEKKLET VQPQENSLAK IQSVGNNLQR VNRVLTGPRS
IQKRHFKEVG KQSTRREEGA QAFVESAAQE KRLGSPVSRE LEQPHIEQGR EKLVGNTVYT
KPSFTQERNA AVSSVLKPFS MGEPSASTPA KALPEVKDRS KDLTHAIFIL ENAKARVKTM
KAAKPSRKKY RFHKSGSRVA HRTPKAKKIR KLRKEGYLDR LMLANRPLLS AAKSLINSQG
AFSSLGDLSL QQNPFLEVFA PSERFIENTN VKDTAARNAF EENVFMESTT MPEGTISENT
TYNPPPEADS AGTAFNLGPT GDQFEIQLTE QLRSLIPSED VRRFISHVIW TLKTDCSDTR
VQLTCAKLIS RTGLLMKLLS EQQEVKASKA EWDTEQWKTE NYINESMEAQ SEQKEQRLSE
LTKEVPGYGY NNKLILAICV TVTLIILITI FCLIEIHSKK RRASKEDNLS PS
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