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Database: UniProt
Entry: F7HD54_CALJA
LinkDB: F7HD54_CALJA
Original site: F7HD54_CALJA 
ID   F7HD54_CALJA            Unreviewed;       691 AA.
AC   F7HD54;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   30-AUG-2017, entry version 36.
DE   SubName: Full=Hyperpolarization activated cyclic nucleotide gated potassium channel 2 {ECO:0000313|Ensembl:ENSCJAP00000023649};
GN   Name=HCN2 {ECO:0000313|Ensembl:ENSCJAP00000023649};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000023649, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000023649, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000023649}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCJAP00000023649}.
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DR   EMBL; ACFV01171096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171097; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171098; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171100; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171102; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171103; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171104; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01171105; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9483.ENSCJAP00000023649; -.
DR   Ensembl; ENSCJAT00000025016; ENSCJAP00000023649; ENSCJAG00000012903.
DR   eggNOG; KOG0498; Eukaryota.
DR   eggNOG; ENOG410XPSE; LUCA.
DR   GeneTree; ENSGT00760000118772; -.
DR   InParanoid; F7HD54; -.
DR   OMA; CPQVARP; -.
DR   OrthoDB; EOG091G0JQU; -.
DR   TreeFam; TF318250; -.
DR   Proteomes; UP000008225; Chromosome 22.
DR   GO; GO:0098855; C:HCN channel complex; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IEA:Ensembl.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071321; P:cellular response to cGMP; IEA:Ensembl.
DR   GO; GO:1990573; P:potassium ion import across plasma membrane; IEA:Ensembl.
DR   GO; GO:0098719; P:sodium ion import across plasma membrane; IEA:Ensembl.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013621; Ion_trans_N.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08412; Ion_trans_N; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     46     70       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    278    301       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1     44       Ion_trans_N. {ECO:0000259|Pfam:PF08412}.
FT   DOMAIN       46    306       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   691 AA;  76627 MW;  12B6C1F76C222FB7 CRC64;
     FGALLQPGVN KFSLRMFGSQ KAVEREQERV KSAGAWIIHP YSDFRFYWDF TMLLFMVGNL
     IIIPVGITFF KDETTAPWIV FNVVSDTFFL MDLVLNFRTG IVIEDNTEII LDPEKIKKKY
     LRTWFVVDFV SSIPVDYGTK AAGPGREGDG AGSSQQGRAI RFWVGLQWHM EWARQGQGMR
     VLGQWGHIFH MTYDLASAVM RICNLISMML LLCHWDGCLQ FLVPMLQDFP RNCWVSINGM
     VNHSWSELYS FALFKAMSHM LCIGYGRQAP ESMTDIWLTM LSMIVGATCY AMFIGHATAL
     IQSLDSSRRQ YQEKGRQISP LGSQFPQEWK LREDVEPEQQ RRALQEGAHL GRLLGPGFRE
     SRAAPPRPLA CSDHRANPGL CRGGWTEMGI GPIAAGLWSW ALKIIREGES GAHPFLRGGV
     ARCLEAKKNF KKLRTRSYLW TSEKHQMKNS GSVRCLLYSL SVDNFNLLEE YPMMRRAFET
     VAIDRLDRIG KKNSILLHKV QHDLNSGVFN NQENAIIQEI VKYDREMVQQ AELGQRVGLF
     PPPPPPQVTS AIATLQQAVA MSFCPQVARP LVGPLALGSP RLVRRPPPGP APRTSPYGGS
     PAAPLAGPAL PARRLSRASR PLSASQPSLP HGAPGPAASA RPASSSTPRL GPTPAARAAA
     PSPDRRDSAS PGPAGGLDPQ DSARSRLSSN L
//
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