ID F7HYA9_CALJA Unreviewed; 630 AA.
AC F7HYA9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Splicing regulatory glutamic acid and lysine rich protein 1 {ECO:0000313|Ensembl:ENSCJAP00000029413.4};
GN Name=SREK1 {ECO:0000313|Ensembl:ENSCJAP00000029413.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000029413.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000029413.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000029413.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_002744950.1; XM_002744904.3.
DR AlphaFoldDB; F7HYA9; -.
DR STRING; 9483.ENSCJAP00000029413; -.
DR Ensembl; ENSCJAT00000031080.5; ENSCJAP00000029413.4; ENSCJAG00000015950.5.
DR GeneID; 100393736; -.
DR KEGG; cjc:100393736; -.
DR CTD; 140890; -.
DR GeneTree; ENSGT00730000110872; -.
DR HOGENOM; CLU_030029_3_0_1; -.
DR InParanoid; F7HYA9; -.
DR OMA; AFNGAMF; -.
DR OrthoDB; 554604at2759; -.
DR Proteomes; UP000008225; Chromosome 2.
DR Bgee; ENSCJAG00000015950; Expressed in ovary and 6 other cell types or tissues.
DR GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12519; RRM1_SREK1; 1.
DR CDD; cd12260; RRM2_SREK1; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034192; SREK1_RRM2.
DR PANTHER; PTHR32343; SERINE/ARGININE-RICH SPLICING FACTOR; 1.
DR PANTHER; PTHR32343:SF71; SPLICING REGULATORY GLUTAMINE_LYSINE-RICH PROTEIN 1; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 19..98
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 182..258
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 289..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..374
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..530
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..608
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 630 AA; 72395 MW; 7CFAFC3C7857233D CRC64;
MNTGAGFGLG LGFGLTPTSV IQVTNLSSAV TSEQMRTLFS FLGEIEELRL YPPDNAPLAF
SSKVCYVKFR DPSSVGVAQH LTNTVFIDRA LIVVPCAEGK IPEESKALSL LAPAPTMTSL
MPGAGLLPIP TPNPLTTLGV SLSSLGAIPA AALDPNIATL GEIPQPPLMG NVDPSKIDEI
RRTVYVGNLN SQTTTADQLL EFFKQVGEVK FVRMAGDETQ PTRFAFVEFA DQNSVPRALA
FNGVMFGDRP LKINHSNNAI VKPPEMTPQA AAKELEEVMK RVREAQSFIS AAIEPESGKS
NERKGGRSRS HTRSKSRSSS KSHSRRKRSQ SKHRSRSHNR SRSRQKDRRR SKSPHKKRSK
SRERRKSRSR SRSRDKRKDT REKIKEKERV KEKDREKERE KEREREKERE KEKERGKNKD
KDRDKEREKD REKDKEKDRE KEREKEHEKD RDKEKEKEQD KEKEREKDRS KEIDEKRKKD
KKSRTPPRSY NASRRSRSSS RERRRRRSRS SSRSPRTSKT IKRKSSRSPS PRSRNKKDKK
REKERDHISE RRERERSTSI RKSSNDRDGK EKLEKSSTSL KEKEHNKEPD SSVSKEVDDK
DAPRTEENKV QHNGNCQLNE ENLSTKTEAV
//
