ID F7I584_CALJA Unreviewed; 1008 AA.
AC F7I584;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=RAB44, member RAS oncogene family {ECO:0000313|Ensembl:ENSCJAP00000029594.4};
GN Name=RAB44 {ECO:0000313|Ensembl:ENSCJAP00000029594.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000029594.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000029594.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000029594.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7I584; -.
DR STRING; 9483.ENSCJAP00000029594; -.
DR Ensembl; ENSCJAT00000031270.5; ENSCJAP00000029594.4; ENSCJAG00000016070.6.
DR eggNOG; KOG0078; Eukaryota.
DR GeneTree; ENSGT00940000160379; -.
DR HOGENOM; CLU_012405_0_0_1; -.
DR InParanoid; F7I584; -.
DR OMA; SEMIFDW; -.
DR TreeFam; TF313199; -.
DR Proteomes; UP000008225; Chromosome 4.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0002553; P:histamine secretion by mast cell; IEA:Ensembl.
DR GO; GO:0097279; P:histamine secretion mediated by IgE immunoglobulin; IEA:Ensembl.
DR CDD; cd00154; Rab; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47977; RAS-RELATED PROTEIN RAB; 1.
DR PANTHER; PTHR47977:SF72; RAS-RELATED PROTEIN RAB-44; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 191..294
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 445..472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..680
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..721
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..750
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 110050 MW; 1C4BEA2E93B9D8F2 CRC64;
METGQRGSRK VRKLGSSRRR QTREPADGED AAVAPEPESW SSQAAAELQA FFQDCGAKER
GFVTREDLAV AKFSFLGGEE KPEMIFDWVD VERKGHLSLE EFNSGLKNIL GSSQSAHRLR
RRKPLPSKRV SATTSFPALE EADDEEKEAF LAFMEQLGTG HLLPKQTEIW QLWGKLRQEE
PQLAGNLAGF VAKMTSCLQE AQAEKEALEL TLRKRDSDHH REVQQLYEEM EQQIHQEKQQ
LQAESDSRGL ALTSQMQDVL EAKELEVQRL AEGHRELEAQ LSHLRSTHQE AASENQQLWE
AKRDLAGRLE EVRGQLQVTK GRLDTARGRV SWQMEEKLSV PGVGEKAPDP QAVSPEEGPL
PGLFGDNDDW DQLLSSFGSP PHGALQLCWS PPPSPRNTPG PQTPRVVRQI SISEPHALLF
VQEPSSDPDR VPRTPPGVTF SVKDSKVMDP DERDVSAEQP VEPRDQDQEL GSRPEGHLLW
GLPGSRVAAA FKVLIPLEDG LPLHWNSPPP QAPAGSSKQI QASDSDDKGP GSWAPPRGAQ
PGAEAGPQEP TETTCTMTEQ ETQPGPSPTT ALEGGGPAKP PRQREALQQD LRATGSERGL
GFQKARALTL GPAEPFQGLA SVGPVPTKRL EQGQADPAVQ EGLPEGLREA HGWVLGLGEL
PSLPHQGLEE EPRAKEGEQV DQGGQDLGSE RSVEAHSLET ANSEHPQQDS LLISLPSATP
QAQVDAEAPA PGKPAPPPMG AQPGAGPQEP KETPPTVTKQ EAQPRPSLMT THTEQGPPHS
REPRVESMLE DPGMDSREAG LIPPPGDPMP GRPQANPDYL FHVIFLGDSN VGKTSFLHLL
HQNSFATGLT ATVGVDFRVK TLLVDNKCFV LQLWDTAGQE RYHSMTRQLL RKADGVVLMY
DVTSQESFGH VRYWLDCLQD AGADGVAILL LGNKMDCEEE RQVPTEAGQQ LAQELGVSFG
ECSAALGHNI LEPVVNLARS LRMQEDSLKG SLVEVAPKRP PKRFGCCS
//
