ID F7IFB5_CALJA Unreviewed; 715 AA.
AC F7IFB5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Calcium-binding and coiled-coil domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040932};
GN Name=CALCOCO1 {ECO:0000313|Ensembl:ENSCJAP00000034908.3};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000034908.3, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000034908.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000034908.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CALCOCO family.
CC {ECO:0000256|ARBA:ARBA00037963}.
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DR AlphaFoldDB; F7IFB5; -.
DR STRING; 9483.ENSCJAP00000034908; -.
DR Ensembl; ENSCJAT00000036861.4; ENSCJAP00000034908.3; ENSCJAG00000018726.5.
DR GeneTree; ENSGT00950000183025; -.
DR HOGENOM; CLU_703890_0_0_1; -.
DR InParanoid; F7IFB5; -.
DR OMA; HNWASND; -.
DR OrthoDB; 3062393at2759; -.
DR Proteomes; UP000008225; Chromosome 9.
DR Bgee; ENSCJAG00000018726; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030374; F:nuclear receptor coactivator activity; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd21967; Zn-C2H2_CALCOCO1; 1.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 6.20.250.40; -; 1.
DR InterPro; IPR012852; CALCOCO1-like.
DR InterPro; IPR041641; CALCOCO1/2_Zn_UBZ1.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR31915:SF5; CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR31915; SKICH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07888; CALCOCO1; 1.
DR Pfam; PF17751; SKICH; 1.
DR Pfam; PF18112; Zn-C2H2_12; 1.
DR PROSITE; PS51905; ZF_UBZ1; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 677..703
FT /note="UBZ1-type"
FT /evidence="ECO:0000259|PROSITE:PS51905"
FT REGION 514..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 146..208
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 251..334
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 387..513
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 576..593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 79715 MW; B1C9C92120862C6E CRC64;
MEESPLSRAP SRGGVNFLNV ARTYIPNTKV ECHYTLPPGT MPSASDWIGI FKVEAACVRD
YHTFVWSSVP ESTTDGSPIH TSVQFQASYL PKPGAQLYQF RYVNRQGRVC GQSPPFQFRE
PRPMDELVTM EEADGGSDIL LVVPKATVLQ NQLDESQQER NDLMQLKLQL EAQVTELRSR
VQELERVLAT ARQEHAELTE QYKGISRSHG EITEERDILS RQQGDHVARI LELEDDIQTI
SEKVLMKEVE LDRVRDTVKA LTREQEKLLG QLKEVQADKE QSEAELQAAQ QENHRLNLEL
LEAKSWQEEQ SAQVERLKDK VAQMKDTLGQ AQQRVAELEP LKEQLRGAQE LAASSQQKAT
LLGEELASAA AARDRTIAEL HRSRLEVAEV NGRLAELSLH LKEEKSQWSK ERAGLLQSVE
AEKDKILKLS AEILRLEKAV QEERTQTQVL KTELAQEKDS SLVQLSESKR ELTELRSALR
VLQKEKEQLQ EEKQELLEYM RKLEARLEKV ADEKWNEDAA TEDEEAAAGL SCPAALTDSE
DESPEDMRLP PYGPCEHGDP GSSPAGPRET SPLVVISQPA PISSHLSGPA EDSSSDSEAE
DEKSVLMAAV QSGGEEANLL LPELGSAFYD MASTIFRRAQ IALLPLSPAP PPSPATSGFT
VGPLSEASTG GPATPTWKEC PICKERFPAE SDKDALEDHM DGHFFFSTQD PFTFE
//
