ID F7IID7_CALJA Unreviewed; 439 AA.
AC F7IID7; A0A5F4W102;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Fibrinogen like 2 {ECO:0000313|Ensembl:ENSCJAP00000071534.2};
DE SubName: Full=Fibroleukin {ECO:0000313|EMBL:JAB24317.1};
GN Name=FGL2 {ECO:0000313|EMBL:JAB24317.1,
GN ECO:0000313|Ensembl:ENSCJAP00000071534.2};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB24317.1};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000071534.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB24317.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Cerebellum {ECO:0000313|EMBL:JAB42720.1}, and Cerebral cortex
RC {ECO:0000313|EMBL:JAB24317.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
RN [3] {ECO:0000313|Ensembl:ENSCJAP00000071534.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; GAMR01009615; JAB24317.1; -; mRNA.
DR EMBL; GAMP01010035; JAB42720.1; -; mRNA.
DR RefSeq; XP_002751716.1; XM_002751670.3.
DR STRING; 9483.ENSCJAP00000071534; -.
DR Ensembl; ENSCJAT00000097706.2; ENSCJAP00000071534.2; ENSCJAG00000068096.2.
DR GeneID; 100393441; -.
DR KEGG; cjc:100393441; -.
DR CTD; 10875; -.
DR eggNOG; KOG2579; Eukaryota.
DR GeneTree; ENSGT00940000157946; -.
DR HOGENOM; CLU_038628_3_0_1; -.
DR OMA; MQRDCAD; -.
DR OrthoDB; 3134470at2759; -.
DR TreeFam; TF336658; -.
DR Proteomes; UP000008225; Chromosome 8.
DR Bgee; ENSCJAG00000068096; Expressed in kidney and 6 other cell types or tissues.
DR GO; GO:0050687; P:negative regulation of defense response to virus; IEA:Ensembl.
DR GO; GO:0002605; P:negative regulation of dendritic cell antigen processing and presentation; IEA:Ensembl.
DR GO; GO:0002617; P:negative regulation of macrophage antigen processing and presentation; IEA:Ensembl.
DR GO; GO:0043381; P:negative regulation of memory T cell differentiation; IEA:Ensembl.
DR GO; GO:0002291; P:T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IEA:Ensembl.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR020837; Fibrinogen_CS.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR19143; FIBRINOGEN/TENASCIN/ANGIOPOEITIN; 1.
DR PANTHER; PTHR19143:SF189; FIBROLEUKIN; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR SMART; SM00186; FBG; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR PROSITE; PS00514; FIBRINOGEN_C_1; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..439
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015091294"
FT DOMAIN 204..436
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 103..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 130..164
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 439 AA; 50495 MW; A647BFB3003562FF CRC64;
MKLANWYWLS SAVLATYGFL VVANNETEEI KDERAKDLCP VRLEGRGKCD EAGECPYQVS
LPRLTIQLPK QFSRIEEVFK EVQNLKDIVN SLKKSCQDCK LQADDNGDPS RNGLLLPSTG
DQGEVGDNRV RELESEVNKL SSELKNAKEE INVLHDRLEK LNLVNMNNIE NYVDSKVANL
TFVVNSLDGK CSKCPSQEQI QSRPVQHLIY KDCSDYYAIG KRSSETYRVT PDPKNRSFEV
YCDMETMGGG WTVLQARLDG STNFTRTWDD YKVGFGNLRR EFWLGNDKIH LLTKSKEMIL
RIDLEDFNGV KLYALYDQFY VANEFLKYRL HVGNYNGTAG DALRFNKHYN HDLKFFTTPD
KDNDRYPSGN CGLYYSSGWW FDACLSANLN GKYYHQKYRG VRNGIFWGTW PGLSEAQPGG
YKSSFKEAKM MIRPKHFKP
//
