ID   F7K0I3_9FIRM            Unreviewed;       792 AA.
AC   F7K0I3;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=ATP-cone domain-containing protein {ECO:0000259|PROSITE:PS51161};
GN   ORFNames=HMPREF0991_02896 {ECO:0000313|EMBL:EGN44706.1};
OS   Lachnospiraceae bacterium 2_1_58FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658082 {ECO:0000313|EMBL:EGN44706.1, ECO:0000313|Proteomes:UP000004820};
RN   [1] {ECO:0000313|EMBL:EGN44706.1, ECO:0000313|Proteomes:UP000004820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2_1_58FAA {ECO:0000313|EMBL:EGN44706.1,
RC   ECO:0000313|Proteomes:UP000004820};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 2_1_58FAA.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGN44706.1}.
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DR   EMBL; ACTO01000048; EGN44706.1; -; Genomic_DNA.
DR   AlphaFoldDB; F7K0I3; -.
DR   PATRIC; fig|658082.3.peg.2905; -.
DR   HOGENOM; CLU_002707_0_2_9; -.
DR   OrthoDB; 9804622at2; -.
DR   Proteomes; UP000004820; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd01675; RNR_III; 1.
DR   CDD; cd02947; TRX_family; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR012833; NrdD.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}.
FT   DOMAIN          2..95
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
SQ   SEQUENCE   792 AA;  90475 MW;  49454F61F09447C6 CRC64;
     MYQVTKRDGE ITEFNLTKIS EAIRKAFEAR EKEYNQDIID LLALKVTADF EPKIKEHKIA
     VEDIQDSVES VLIKAGYADV AKGYILYRKQ REKIRNLNST LLDYKEIVDS YVKVTDWRVK
     ENSTVTYSVG GLILSNSGAI TANYWLSEIY DEEIGKAHKN ADIHIHDLSM LTGYCAGWSL
     KQLIQEGLGG VTGRITSAPA KHLSVLCNQM VNFLGIMQNE WAGAQAFSSF DTYLAPFVKA
     DHLTYREVKK CIESFIFGVN IPSRWGTQAP FSNITLDWTV PNDLANLPAI VGGKEQDFTY
     GDCKEEMDMI NRAFIETMIE GDAQGRGFQY PIPTYSITKD FDWSDTENNR LLFEMTAKYG
     TPYFSNYINS DMEPSDVRSM CCRLRLDLRE LRKKSGGFFG SGESTGSVGV VTINMPRIAY
     LSKNEEEFYE RLDKMMDIAA RSLHIKRVVI SRLLDEGLYP YTKRYLGSFD NHFSTIGLIG
     MNEAGLNAKW IRKDLTHPET QKFTKDVLNH MRERLSDYQE EYGDLYNLEA TPAESTTYRL
     AKHDVEQFPD IITAAEDCGT PYYTNSSHLP VGYTEDVFAA LDIQDELQTL YTSGTVFHTF
     LGEKLPDWKS AAALVRKIAE NYKLPYYTMS PTYSICKNHG YISGEQYTCP ICGEETEVYS
     RITGYYRPVK NWNDGKLQEF KERKVYDVEH SHVKQENFRE TEQEEEQRIF EEVNTEEGKV
     LLFTTKTCPN CKLAKDSLEK ANISYEVVDA GENEELVRKY GVMQAPTLIV IKEEGVQKLA
     NASNIRAFAE KR
//