ID F7K0T4_9FIRM Unreviewed; 861 AA.
AC F7K0T4;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=HMPREF0991_03003 {ECO:0000313|EMBL:EGN44506.1};
OS Lachnospiraceae bacterium 2_1_58FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658082 {ECO:0000313|EMBL:EGN44506.1, ECO:0000313|Proteomes:UP000004820};
RN [1] {ECO:0000313|EMBL:EGN44506.1, ECO:0000313|Proteomes:UP000004820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_1_58FAA {ECO:0000313|EMBL:EGN44506.1,
RC ECO:0000313|Proteomes:UP000004820};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 2_1_58FAA.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN44506.1}.
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DR EMBL; ACTO01000050; EGN44506.1; -; Genomic_DNA.
DR AlphaFoldDB; F7K0T4; -.
DR PATRIC; fig|658082.3.peg.3015; -.
DR HOGENOM; CLU_002926_1_1_9; -.
DR OrthoDB; 9761045at2; -.
DR Proteomes; UP000004820; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF6; ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 132..295
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 304..397
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 405..765
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 767..837
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 861 AA; 97795 MW; E2B41973406DF2B3 CRC64;
MLKICRLTVE NMETGCVTDN PQPRVSYCLE SDRQNVTLKK AVISIGDWKK ETDCQIAVPY
EGSRLQPFTK YAVRVEAEDD AGERAWASTE FETGRMDTIW SGRWITDGEY RFKEAKISPK
TMTFRTRFSC EKEIASARLY VTALGIYELL LNGEKVGQDY FAPGFTSYRN QLQYQTYDVT
DMLNDRNELL AVVGGGWAVG SFTYKRRNRV YAKRQALLGE LRILYTDGTG ETIGTNEEWE
VTEEGNYKET EFYNGEVYDA TVDLEKISWK KASFEQVKIH PKIMAQYGAP VRAHEEFRPV
QITRAKSGML IYDFGQNFAG VIHAAIRGRQ GQKVEFRHAE ILMDGELYTE PLRTAKQEAV
YICKDGEQTY SPKMTYMGFR YVGVRGIEED QLELTALALY SDVEDNGNFS CSNELINQLQ
NSIRWGAKSN FVDIPTDCPQ RDERMGWTGD IALFAPTAAY NFNISRFLEK WLLDVKAEQN
KGGGIPVTVP LVRVPLQWEI MIPMAVDHWG DVCILAPWAE YLVRGDRGLL ERMYPVMKKY
LKACKFWAEL FSAGKHRRIW KLLHHYGDWC APGVGMWEWM GRGKWTATAC MANSSRILAK
IADILGQEED AKYYRKLSQE TGEAYREILM KADCTVKKEF QTAYVLPLYY QMLSGEDKKK
TAANLARLVK KDGYHITTGF PGTPYVLFAL ADNGYEEEAF KMLLTDTCPS WLYEMKVGGT
TIWERWDALR EDGTCNTGKD DGTGGMVSFN HYASGAVGDF LYRRIAGIEA TEGGYRSFRI
QPLTGGNLKW AKGSVNTAYG TVSSEWKIED GMFTIQVQVP VGTTCTLVMP GNTQKVLGSG
TYTLKEAIRE RNDRNGKESV F
//
