ID   F7K230_9FIRM            Unreviewed;       323 AA.
AC   F7K230;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Dihydrodipicolinate synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF0991_03443 {ECO:0000313|EMBL:EGN42556.1};
OS   Lachnospiraceae bacterium 2_1_58FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658082 {ECO:0000313|EMBL:EGN42556.1, ECO:0000313|Proteomes:UP000004820};
RN   [1] {ECO:0000313|EMBL:EGN42556.1, ECO:0000313|Proteomes:UP000004820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2_1_58FAA {ECO:0000313|EMBL:EGN42556.1,
RC   ECO:0000313|Proteomes:UP000004820};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 2_1_58FAA.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGN42556.1}.
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DR   EMBL; ACTO01000069; EGN42556.1; -; Genomic_DNA.
DR   AlphaFoldDB; F7K230; -.
DR   PATRIC; fig|658082.3.peg.3446; -.
DR   HOGENOM; CLU_049343_4_1_9; -.
DR   OrthoDB; 9782828at2; -.
DR   Proteomes; UP000004820; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   PANTHER; PTHR12128:SF38; DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G00110); 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365}.
FT   BINDING         53
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   323 AA;  36308 MW;  362BF4378943609A CRC64;
     MAKVKNFKTI FPAVSVPLNE DYSINEPEFR AYLRWIKSFY GKGMDGLVCN GHTGEITGLT
     RAERKRVVEI CAEECGDVMT IISGVNCENT AESIEMAKEA KEAGADGILL MPPHMWLRFG
     MNPDAPFEYV KDVAEGADID IIIHLYPATS KAFYPVETLI KMCKEIDHVK CIKMGTRVTS
     IYEHDVRLLR QECPDISLIT CHDETLCVSW FPGMDGALIG FAGCVPEIIC PAREVFANPD
     KHTLKEAQDW SDRIYHISQA IYGGGQPSGE AHARLKEALY QRGIFSNALM RKPVLPLNQE
     EKDWVSLGLE RSQLPKVDME QYK
//