ID F7KQV1_9FIRM Unreviewed; 704 AA.
AC F7KQV1;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=HMPREF0993_01353 {ECO:0000313|EMBL:EGN39661.1};
OS Lachnospiraceae bacterium 5_1_57FAA.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=658085 {ECO:0000313|EMBL:EGN39661.1, ECO:0000313|Proteomes:UP000005617};
RN [1] {ECO:0000313|EMBL:EGN39661.1, ECO:0000313|Proteomes:UP000005617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5_1_57FAA {ECO:0000313|EMBL:EGN39661.1,
RC ECO:0000313|Proteomes:UP000005617};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 5_1_57FAA.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN39661.1}.
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DR EMBL; ACTR01000010; EGN39661.1; -; Genomic_DNA.
DR AlphaFoldDB; F7KQV1; -.
DR PATRIC; fig|658085.3.peg.1396; -.
DR HOGENOM; CLU_007352_0_0_9; -.
DR Proteomes; UP000005617; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005617};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 548..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 574..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 615..638
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..332
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 467..676
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 704 AA; 77496 MW; D7A26AD12489405B CRC64;
MMVKIGKKIV KYRVVVFILG LLLLIPSALG YLKTRVNYDI LYYLPDNIET MKGQDILMKD
FGKGAFAMEV VEGMTTKQEA KVKDKIEKVD GVAEVIWYDS IADVSELPIN ALPGEIKDVF
NTKDATLMAI FFDDTTSADS TMDAITEIRS ITNKQCYLSS MSAVVTDIKA LSEKETPLYV
LIAVVLSCVV LSLFMDCWII PVFFLASIGM AILYNMGTNY FLGEISYITK ALSAVLQLGV
TMDYSIFLWH SYQENQLRFP DDKERAMAHA ISNTFSSVVG SSITTVAGFI ALCFMSFTLG
KDLGVVMAKG VIFGVISCVT LLPSMILIFD KAIQKTSHRS LMPKMEKPAR MISKYYGVFI
AIFLIVLGPA LWGYTKAEVY YNLDATLPKY LDSIKANEKL SKEFDMNATH MVLADADLAP
KEAKAMLDEM SDVKGVKFAL GLDSLLGPAI PRDMIPDELT DALREGNYQL ILVQSEYKVA
TDAVNKQCTK LNNIIKKHDS SAMLIGEAPC TKDLITITDK DFKVVSAISI VAIFIIIALV
FKSISLPVIL VSVIEFAIFI NLGIPYYTGT KMPFIASIVI GTIQLGATVD YAILMTTRYK
KERCRGQGKK EAIRIALSTS ISSVIVSALG FFAATFGVGL YSDIDMISAL CTLMARGAII
SMFTVIFILP SMLMVFDGAI CKTTLDMRGK VKKTNKVKDS VVKA
//
