ID   F7KRY2_9FIRM            Unreviewed;       788 AA.
AC   F7KRY2;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   RecName: Full=ATP-cone domain-containing protein {ECO:0000259|PROSITE:PS51161};
GN   ORFNames=HMPREF0993_01726 {ECO:0000313|EMBL:EGN39105.1};
OS   Lachnospiraceae bacterium 5_1_57FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658085 {ECO:0000313|EMBL:EGN39105.1, ECO:0000313|Proteomes:UP000005617};
RN   [1] {ECO:0000313|EMBL:EGN39105.1, ECO:0000313|Proteomes:UP000005617}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5_1_57FAA {ECO:0000313|EMBL:EGN39105.1,
RC   ECO:0000313|Proteomes:UP000005617};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA   Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA   Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA   Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 5_1_57FAA.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGN39105.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACTR01000013; EGN39105.1; -; Genomic_DNA.
DR   AlphaFoldDB; F7KRY2; -.
DR   PATRIC; fig|658085.3.peg.1790; -.
DR   HOGENOM; CLU_002707_0_2_9; -.
DR   Proteomes; UP000005617; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd02976; NrdH; 1.
DR   CDD; cd01675; RNR_III; 1.
DR   Gene3D; 3.20.70.20; -; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR005144; ATP-cone_dom.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR012833; NrdD.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   NCBIfam; TIGR02487; NrdD; 1.
DR   PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF03477; ATP-cone; 1.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   Pfam; PF13597; NRDD; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51161; ATP_CONE; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00492};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000005617}.
FT   DOMAIN          2..95
FT                   /note="ATP-cone"
FT                   /evidence="ECO:0000259|PROSITE:PS51161"
SQ   SEQUENCE   788 AA;  89307 MW;  C3613C0312B0808F CRC64;
     MYRVMKRDGQ VAEFTLSKIG VAIEKAFKAQ EKEYNQDIID LLALKVTADF EPKIKDSLIN
     VEDIQDSVEA VLIKAGYADV AKGYILYRKQ REKIRNLNST MLDYKEIVDS YVKITDWRVK
     ENSTVTYSVG GLILSNSGAI TANYWLSEIY DEEIGQAHRN ADIHIHDLSM LTGYCAGWSL
     KQLIQEGLGG IPGKISSSPA KHLSVLCNQM VNFLGIMQNE WAGAQAFSSF DTYLAPFVKA
     DNLSYHEVKK CIESFIYGVN TPSRWGTQAP FSNITLDWTV PNDLANLPAI IGGKEMDFTY
     GDCKKEMDMV NKAFIEIMIE GDAHGRGFQY PIPTYSITSD FDWSDTENNR LLFEMTAKYG
     TPYFSNYINS DMEPSDVRSM CCRLRLDLRE LRKKSGGFFG SGESTGSVGV VTINMPRIAY
     QSANEEEFFA RLDKMMDISA RSLHVKRVVI SKLMNEGLYP YTKRYLGTFD NHFSTIGLIG
     MNEAGLNANW IGKDMTHEET QEFTKKVLNH MRERLSAYQE EYGDLYNLEA TPAESTTYRF
     AKHDKAQFPD IITAAEGDGT PYYTNSSHLP VGYTEDVFEA LDIQDELQTL YTSGTVFHAF
     LGEKLPSWKA AASLVRKIAE NYKLPYYTMS PTYSICKNHG YLNGEQYSCP ECGETTEVYS
     RITGYYRPVQ NWNDGKAQEF KDRKVYDLSH SKLQVKAKAE EHIDEVLKQE AQEPKKLLFT
     TKTCPNCIMA KTMLEKANID YEIVDAQEHA DLVEKYGVKQ APTLIVIQEG KVEKLANASN
     IKKYIESN
//