ID F7L0H4_9FUSO Unreviewed; 149 AA.
AC F7L0H4;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Transcriptional repressor NrdR {ECO:0000256|HAMAP-Rule:MF_00440};
GN Name=nrdR {ECO:0000256|HAMAP-Rule:MF_00440};
GN ORFNames=HMPREF0401_01345 {ECO:0000313|EMBL:EGN66977.1};
OS Fusobacterium animalis 11_3_2.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=457403 {ECO:0000313|EMBL:EGN66977.1, ECO:0000313|Proteomes:UP000004160};
RN [1] {ECO:0000313|EMBL:EGN66977.1, ECO:0000313|Proteomes:UP000004160}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11_3_2 {ECO:0000313|EMBL:EGN66977.1,
RC ECO:0000313|Proteomes:UP000004160};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Sibley C.D., White A.P.,
RA Crowley S., Surette M., Strauss J.C., Ambrose C.E., Allen-Vercoe E.,
RA Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA Alvarado L., Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z.,
RA Dunbar C., Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P.,
RA Mehta T., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusobacterium sp. 11_3_2.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes. {ECO:0000256|HAMAP-Rule:MF_00440}.
CC -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000256|HAMAP-
CC Rule:MF_00440}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGN66977.1}.
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DR EMBL; ACUO01000019; EGN66977.1; -; Genomic_DNA.
DR RefSeq; WP_005905337.1; NZ_GL945392.1.
DR AlphaFoldDB; F7L0H4; -.
DR GeneID; 79809139; -.
DR PATRIC; fig|457403.8.peg.1359; -.
DR HOGENOM; CLU_108412_0_0_0; -.
DR Proteomes; UP000004160; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00440; NrdR; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR003796; RNR_NrdR-like.
DR NCBIfam; TIGR00244; transcriptional regulator NrdR; 1.
DR PANTHER; PTHR30455; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR PANTHER; PTHR30455:SF2; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|HAMAP-Rule:MF_00440};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00440};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00440}.
FT DOMAIN 48..138
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
SQ SEQUENCE 149 AA; 17628 MW; D824B33373605C0A CRC64;
MKCPFCSSED TKVIDSRTTI DGSTKRRREC NNCLKRFSTY ERFEESPIYV VKKDNRRVKY
EREKLLRGLT FATVKRNISR EQLDKIITDI ERGLQNSLVS EISSKELGEK VLEKLRELDQ
VAYVRFASVY KEFNDIKSFI EIVEEIKKD
//
