ID F7M9J8_9BACE Unreviewed; 432 AA.
AC F7M9J8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Alpha-L-fucosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF0127_04132 {ECO:0000313|EMBL:EGM97359.1};
OS Bacteroides sp. 1_1_30.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=457387 {ECO:0000313|EMBL:EGM97359.1, ECO:0000313|Proteomes:UP000004085};
RN [1] {ECO:0000313|EMBL:EGM97359.1, ECO:0000313|Proteomes:UP000004085}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1_1_30 {ECO:0000313|EMBL:EGM97359.1,
RC ECO:0000313|Proteomes:UP000004085};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacteroides sp. 1_1_30.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGM97359.1}.
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DR EMBL; ADCL01000085; EGM97359.1; -; Genomic_DNA.
DR RefSeq; WP_008644769.1; NZ_GL945102.1.
DR AlphaFoldDB; F7M9J8; -.
DR PATRIC; fig|457387.3.peg.4204; -.
DR HOGENOM; CLU_002934_0_2_10; -.
DR Proteomes; UP000004085; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..432
FT /note="Alpha-L-fucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003359083"
FT SITE 277
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 432 AA; 49331 MW; 15E80203E41AC609 CRC64;
MKTRFITFLL LFVMNLGVFA QSSYQPTEEN LKARQEFQDN KFGIFLHWGL YAMLATGEWT
MTNNNLNYKE YAKLAGGFYP SKFDADKWVE AIKASGAKYI CFTTRHHEGF SMFDTKYSDY
NVVKATPFKR DIVKELAAAC AKQGIKLHFY YSHLDWARED YPWGRTGQGT GRLNSKGDWK
SYYQFMNNQL TELLTNYGPI GAIWFDGWWD QPKTFNWELP EQYALIHKLQ PGCLVGNNHH
QTPFDGEDIQ IFERDLPGEN ASGLSGQEVS RLPLETCETM NGMWGYKITD QNYKSTKTLI
HYLVKAAGKN ANLLMNIGPQ PDGELPAVAV QRLAEMGEWM KQYGETIYGT RSGAVAPHDW
GVTTQKGNKL YVHILDLKDA ALFLPLSDKK VKKAVLFKDQ SPVRFTKTKA GVLLEFAEVP
KDIDYVVELT ID
//
