ID F7R0T0_9LACO Unreviewed; 470 AA.
AC F7R0T0;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=LRU_01170 {ECO:0000313|EMBL:EGM51656.1};
OS Ligilactobacillus ruminis SPM0211.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1040964 {ECO:0000313|EMBL:EGM51656.1, ECO:0000313|Proteomes:UP000002971};
RN [1] {ECO:0000313|EMBL:EGM51656.1, ECO:0000313|Proteomes:UP000002971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SPM0211 {ECO:0000313|EMBL:EGM51656.1,
RC ECO:0000313|Proteomes:UP000002971};
RX PubMed=21742873; DOI=10.1128/JB.05601-11;
RA Lee S., Cho Y.J., Lee A.H., Chun J., Ha N.J., Ko G.;
RT "Genome Sequence of Lactobacillus ruminis SPM0211, Isolated from a Fecal
RT Sample from a Healthy Korean.";
RL J. Bacteriol. 193:5034-5034(2011).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGM51656.1}.
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DR EMBL; AFOJ01000005; EGM51656.1; -; Genomic_DNA.
DR AlphaFoldDB; F7R0T0; -.
DR Proteomes; UP000002971; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR010810; Flagellin_hook_IN_motif.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07196; Flagellin_IN; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:EGM51656.1};
KW Cilium {ECO:0000313|EMBL:EGM51656.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:EGM51656.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 8..99
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 219..455
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 412..439
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 470 AA; 50234 MW; B3B54A6D1D022E0D CRC64;
MGQYTGITSD TIDQLLQSDE LRKTVIQNKI DKINTKSQAW TDISTRLGNL TSKLDVLQDE
ATYQTKKVTS SDDTIATISG TSDSMEGSYD LVVKQLATSS KITGGVVSKA DGTTKISTKD
ALGYSGKLTI TNGATDGSDT ALTVEIDVKA TDSLKDIANA INNAKDPSDS TGTKGAGLKA
TIVNNQLVIS SEEMGDRTLT IGGDLKDSLG FANSQTTRGQ SAKFTLDGIE MERNSNSPTD
VIDGVTLNFK KDDASKTITL GLTNDTDKEL SAVKDFVSQY NSVMSFLSEK MDVGDPSKSD
NTTGALAGDS TLISLQSKLQ STVLGGKSVN GVSASTLGLS VDRNGTLSLD ETKFKAQLAK
NPNAVKDFFF VDTSTKYAAE KTGTGYTADF KAVIDRYTST KSGSEGVISL RKSSYQSEIK
DYNKQIERIT EQIATKRARY VTMFTNLDTA IGNLQSQFSY FQSQNSSSNS
//
