ID F7SX65_9BURK Unreviewed; 631 AA.
AC F7SX65;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Sulfatase family protein 11 {ECO:0000313|EMBL:EGP47402.1};
GN ORFNames=AXXA_06603 {ECO:0000313|EMBL:EGP47402.1};
OS Achromobacter insuavis AXX-A.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=1003200 {ECO:0000313|EMBL:EGP47402.1, ECO:0000313|Proteomes:UP000004853};
RN [1] {ECO:0000313|EMBL:EGP47402.1, ECO:0000313|Proteomes:UP000004853}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AXX-A {ECO:0000313|EMBL:EGP47402.1,
RC ECO:0000313|Proteomes:UP000004853};
RA Bador J., Amoureux L., Neuwirth C.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGP47402.1}.
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DR EMBL; AFRQ01000031; EGP47402.1; -; Genomic_DNA.
DR RefSeq; WP_006391376.1; NZ_GL982453.1.
DR AlphaFoldDB; F7SX65; -.
DR PATRIC; fig|1003200.3.peg.1295; -.
DR eggNOG; COG1368; Bacteria.
DR HOGENOM; CLU_014653_3_1_4; -.
DR OrthoDB; 9760224at2; -.
DR Proteomes; UP000004853; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 126..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 272..537
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 318
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 279
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 434
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 487
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 488
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 631 AA; 70817 MW; FE315852EC87E349 CRC64;
MRRLTLRFIL SVLVLLTLSR LGLSLWMWDR VEAAGGLWPV LFGGLRIDVC LLSMVIALPA
VFSPWLGHRP WAARVTAWWF RVWWMLYVLL EVSTPQFIAE YDTRPNRLYF IYLLNPKEVG
SMLWQGYKGV LLAALVVLLV AAWLAVKLFP ARVRDPFLAW WKRPLASLAI LALVVLGARG
TLEHRPINPA KVAFSSDAMV NSLALNSLYS VFDAAYRMRD ERSSAAMYPK MPVDEMNAIV
RDKAGLTGAP LDARYPSLHE QKATVRRDKP LNLVIILQES LGAQYVGSLG GKDLTPNIDR
LGKEGWMFHR AYATGTRSVR GIEAVTAGFL PSVADAVVKL PRSQTGFFTL AQALGKHGYH
SRFVYGGESH FDNMRAFFLG NGFNEVVDRP KFENPVFEGS WGASDEDMFT QVDRLLRADG
DKPVFTLAFS VSNHSPWEYP AGRIQPVGDP ASVDNTVRYA DWALGQFFDK ARKAPYWDNT
VFLVIADHDS RVYGSIPVPV RHFQIPALIL GAGIAPRQDE RIVSQIDMAP TLLSLIGLDN
VNPMLGADLT QRDPNRALMQ YADNFGYLQG DKLLVLEPSK APREFRYRAA PVGQDETYEP
VESADDALTK EALAHALWAS WVYREEKYRL P
//
