ID F7T5Z2_9BURK Unreviewed; 347 AA.
AC F7T5Z2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=2-oxoisovalerate dehydrogenase, E1 component subunit beta {ECO:0000313|EMBL:EGP44257.1};
GN ORFNames=AXXA_21860 {ECO:0000313|EMBL:EGP44257.1};
OS Achromobacter insuavis AXX-A.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=1003200 {ECO:0000313|EMBL:EGP44257.1, ECO:0000313|Proteomes:UP000004853};
RN [1] {ECO:0000313|EMBL:EGP44257.1, ECO:0000313|Proteomes:UP000004853}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AXX-A {ECO:0000313|EMBL:EGP44257.1,
RC ECO:0000313|Proteomes:UP000004853};
RA Bador J., Amoureux L., Neuwirth C.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGP44257.1}.
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DR EMBL; AFRQ01000091; EGP44257.1; -; Genomic_DNA.
DR RefSeq; WP_006394349.1; NZ_GL982453.1.
DR AlphaFoldDB; F7T5Z2; -.
DR PATRIC; fig|1003200.3.peg.4337; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_4; -.
DR OrthoDB; 9780894at2; -.
DR Proteomes; UP000004853; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
FT DOMAIN 14..189
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 347 AA; 37739 MW; 2FBFBBFB8DCFA075 CRC64;
MAIDNNGGPA SAPMTMIQAL RSAMDVMLER DGNVVVFGQD VGYFGGVFRC TEGLQAKYGS
SRVFDTPISE GGIVGVAVGM GAYGLRPVCE IQFADYFYPA SDQIVSEAAR LRYRSVGEFI
APMTIRMPCG GGIYGGQTHS QSPEAMFTQV CGLRTVMPSN PYDAKGLLIA SIENDDPVIF
LEPKRLYNGP FDGHHDRPVT PWTGRPGSVV PTGYYTVPLD TAAIVRPGNA LTVLTYGTTV
HVSLTAAEET GIDAEVIDLR SLWPLDLETI VNSVRKTGRC VVVHEATRTC GYGAELISLV
QEHCFHHLEA PVERVTGWDT PYPHAQEWAY FPGPRRVGEA FKRAMEV
//
