ID F7VLQ8_SORMK Unreviewed; 2316 AA.
AC F7VLQ8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=Putative RhoGEF group protein {ECO:0000313|EMBL:CCC06436.1};
GN ORFNames=SMAC_04827 {ECO:0000313|EMBL:CCC06436.1};
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC06436.1, ECO:0000313|Proteomes:UP000001881};
RN [1] {ECO:0000313|EMBL:CCC06436.1, ECO:0000313|Proteomes:UP000001881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC {ECO:0000313|Proteomes:UP000001881};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CCC06436.1};
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC06436.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CABT02000001; CCC06436.1; -; Genomic_DNA.
DR RefSeq; XP_003347521.1; XM_003347473.1.
DR STRING; 771870.F7VLQ8; -.
DR GeneID; 10804954; -.
DR KEGG; smp:SMAC_04827; -.
DR VEuPathDB; FungiDB:SMAC_04827; -.
DR eggNOG; KOG3519; Eukaryota.
DR HOGENOM; CLU_001112_0_0_1; -.
DR InParanoid; F7VLQ8; -.
DR OMA; DQVGWIW; -.
DR OrthoDB; 25601at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd07589; BAR_DNMBP; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001881};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1485..1713
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1747..1977
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 86..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 986..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1059..1103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1177..1221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1242..1282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1298..1432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1556..1599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1989..2029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2063..2183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2200..2233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..541
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 834..868
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..974
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1064..1078
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1259..1282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1316..1341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1358..1373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1989..2012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2069..2183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2200..2214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2316 AA; 251716 MW; 9C50B6FF626ECF51 CRC64;
MDHGSIQADE AASRTSLQIQ NHDPRSSTHE LMGSSDSHHH HPHHTRSQSQ SQSQYNRHHH
HNYHSSLDNI DRRHPDLYQY LQEAESPHGH NHGHHSHTHT RPPQARRDSH QQDHQSYFPE
HSRQSSPTHP SAPAPALDFE PRPSHLASFS ASYTSYHSAS RPPSRRQSPL ASPLLKSPLA
SPRLTKSPSR TPLASPSASG HSLNQKIPFA SHAAAVNLQA FAANARVPDS LDVGVDEEED
PDNFYRSFGT ESDAVAAVTT TTPNHTTDLD LDLDPMKKSS TSATLPPLQE HKPQTQSPSS
PRSPSNGALK PSPLPAATHA ATHAAVAGTA KMSSGRSAHT NPPPSASGAR SGLRSASNPV
DDRLGGNGRP ALTTANSYGT AGGAYPPGRS VKDLTKKFNQ TGTSHNSHNN NPSQQRGQQQ
SRPLRDPTTF TSTLSAASTI KAGRSPSVGA RAASYSARSS NTTTTTTTTT TTTASGSATT
SSIATSIRRS RGDPTTNNAG SPSQTLYGAR SRSIPRPRPK LSTDDRITNR NSQSFANRIS
KPRNNGGAAA NGPASRSLPQ LSPTTGLPLQ SLSRSNGLLF GEILPDEQDE VTAGFGIQGH
LGVVGGGRPR RTSESSIHDL TRPGPRLRSS SHSDMGDMEP QSPTDWYRGA ASALPDSSAR
VAKNHSRAHS DAVVSSSSSK SSNTRSGRGT ATTSSRAVGN TGRTTPSTPT TPLSSTSRLP
VMVKRASISE SHGRSSPVST RSNSPAAALK YGQTPTSGRS SRQQHGIPAS RAKTPATRSS
TPSTPATATA KRSQTSNRKA APSNIATPSS SSNNNNGRLN AYVAVPAPKL SPSLRSSRPR
QSVATATTAA SRMKSSTGRP TSPDKSNRRA GSRAADNVAT IRRRKLSVGP IDFAQRRETI
KLAYSKTIKD QQAKEAREAA ADKRKKDMEA VTRAKAKAEA AALAALPSAK SSSDSVHRRA
SEAGRHTDKK GLEEPLKLIT NLPVIQTPAQ PPASNGRDSP TLGIPGGFVD SDDELDIPIP
QSAISVATAV TEFEEEEQTE PPRPQSLEAI DYALGNIVID QPPSPRTLEP PEPAPPLASP
LSTHSKRLSY HSPFDDDDDV DDDDDVSIEI ALDTHSQQPT PTRGDFTATK PTTMVPVQPD
AEDEYVPQPY TYSSQNYETT VTILGPENDF RPLYKDQARD TMPPSGLHHA DEPPLNETLG
ATGSGHSHSQ HQQHQHQQQR EEPRIFYIGP HLRDNIASLR DSTFTLSDNG DPYDAHPPST
AEYQQTPDSS HSNSLAVPAY LSPGNRLSQH SAWTDFSFGS DDQNAALDSQ DPRDSRQFKQ
QQQQTEPEPP ASYNNFDRNR SSLRRPPPPR SPELSPLDQP PRASTSSMLA DKADPRQSSE
FDRDNSAAQK RIPLVSHQTA PARPAAANNY DDLDESTYEV LSRPNSYPHT HDEKEFGTAI
ISSPPSAGQF SFETVDRSHL SRTESKSISS EATDNLTQEQ KRLRQRQLVI RELIDTEEIF
VRDMSVVEEI YKGTAEACPQ LDSKTIKLIF RNTDDIIAFH LTFLAQLKDG AASVYQPKGR
KSPTFAHEAS SKDSDTTTLA SINSGGTMNK QELDDDKDRQ TSLGPLFTKN IDQLKAVHEV
YLRTSDLSAK RLIQIQEDDA VKVWLNECSE GAKELTAAWS LDSLLIKPMQ RLTKYPDIIA
HLLKYTPADH PDRDALVNAK STVISAIDEI NRTKRNFELV GQIVGNRKRK DSDVRAGLAR
AFGKRVDKLQ GASNRAPEDE EYAKLHERFG DEFLRLQVVL RDVEFYTRSA STYVHEFLQY
VTAMELVMRL QPSRDYAHIE SRWVQFSVSM RDMEKILDKH LVDVRKHVIE PFEQVIKCYQ
NPGLAIKKRA KRRLDYERYM QLKANGKKID KTLAEAVEQY EALDDTLKKE LPKLSNLTAE
IGNICLAKFV NIQAAWYSTW KEKVKSPLAD LDHVPDLPEI VKTFQRDFTE QVERAGQLVI
LKPVSLRGRT SQSTSDDIGS GSVLSKTRSR PSELLTPRGR GLSINSDYVP SLPTPDVLGR
FDLSPTGTTG SALPSPGQYY RDFYSGLSNG HHSRGNSTAP LSPDPSSSSA PRSVPATHAT
STTGGYSTRP TTGRSFDSGS LPRQSTDSYS AQSASGGTHH TSTHSHNSQH GGVAHSGSGH
TLSRRGSYTS SHHNYATSEP RRQSGLFHSA LPMDDADELD EHHHHAEAEA GPSGHSGHDM
HMSGGAGAGS TSGGGSMFIS AEAAAEANVM WLAASLFEFN IETTKHEGGY PYLTYQAGEI
FDVVAEKGEL WLAKNQDDPT NVIGWIWSKH FAKLAE
//
