ID F7W133_SORMK Unreviewed; 521 AA.
AC F7W133;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 03-MAY-2023, entry version 40.
DE SubName: Full=WGS project CABT00000000 data, contig 2.18 {ECO:0000313|EMBL:CCC11485.1};
GN ORFNames=SMAC_02143 {ECO:0000313|EMBL:CCC11485.1};
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC11485.1, ECO:0000313|Proteomes:UP000001881};
RN [1] {ECO:0000313|EMBL:CCC11485.1, ECO:0000313|Proteomes:UP000001881}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC {ECO:0000313|Proteomes:UP000001881};
RC TISSUE=Mycelium {ECO:0000313|EMBL:CCC11485.1};
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., Poeggeler S.,
RA Read N., Seiler S., Smith K., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the INSIG family.
CC {ECO:0000256|ARBA:ARBA00007475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCC11485.1}.
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DR EMBL; CABT02000018; CCC11485.1; -; Genomic_DNA.
DR RefSeq; XP_003350430.1; XM_003350382.1.
DR STRING; 771870.F7W133; -.
DR GeneID; 10807982; -.
DR KEGG; smp:SMAC_02143; -.
DR VEuPathDB; FungiDB:SMAC_02143; -.
DR eggNOG; KOG4363; Eukaryota.
DR HOGENOM; CLU_039316_1_0_1; -.
DR InParanoid; F7W133; -.
DR OMA; LPWTSTM; -.
DR OrthoDB; 2730354at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR025929; INSIG_fam.
DR PANTHER; PTHR15301; INSULIN-INDUCED GENE 1; 1.
DR PANTHER; PTHR15301:SF3; PROTEIN NSG1-RELATED; 1.
DR Pfam; PF07281; INSIG; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001881};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 55453 MW; 3A4C67362FF8C1F8 CRC64;
MDQNSNGGTT DGPKIFRPIP RRPFNLASPP MISRKDESPS PAPGRDSNTS PQPRITAADL
RFLLDPRSPF NTSASPAGSG AVTSGLDSSN ISRATSFRNL TSSTLFGIFS DPSEPGTAAT
TPGVGRSASN LRNGFYFGEQ LKEETEDETD DAANVLGIAG DARDEDDDDD ETYQETITFR
PKRQRRVSSI TSTIPTFRGE SSSSDINSGN INNNSPVMGL LWSLLRTILL FALGMGYGVL
VTRLPNGDSV TGGYGWRYLT FWGAXXXXXX XXXXXXXXXA VLGRLLPWFD QVWEETFGKR
ARVTKQEKER RRAAAAAEAA AALKSSVSAT LLPTETESST GEGITSPPEA DWPLVVRSIG
AFVGIVFAIR RLPWTSTMQV SITLALANPF LWYLIDRSKP GFLLSAAVGV TGSAILMGLG
DPDMMPAPVA GGMGAYHDHI LTNGQPAMGV LNGTTSRLPR DATGRMGGGA MGGASGNAAV
IETGIWMLSV LFCSCVCFGN IGRRLALNKS AASRGRWGGV R
//
