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Database: UniProt
Entry: F7W9E1_SORMK
LinkDB: F7W9E1_SORMK
Original site: F7W9E1_SORMK 
ID   F7W9E1_SORMK            Unreviewed;       862 AA.
AC   F7W9E1;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   07-JUN-2017, entry version 25.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=SMAC_08441 {ECO:0000313|EMBL:CCC13932.1};
OS   Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) /
OS   K-hell).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae;
OC   Sordaria.
OX   NCBI_TaxID=771870 {ECO:0000313|EMBL:CCC13932.1, ECO:0000313|Proteomes:UP000001881};
RN   [1] {ECO:0000313|EMBL:CCC13932.1, ECO:0000313|Proteomes:UP000001881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell
RC   {ECO:0000313|Proteomes:UP000001881};
RC   TISSUE=Mycelium {ECO:0000313|EMBL:CCC13932.1};
RX   PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA   Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K.,
RA   Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D.,
RA   Poeggeler S., Read N., Seiler S., Smith K., Zickler D., Kueck U.,
RA   Freitag M.;
RT   "De novo assembly of a 40 Mb eukaryotic genome from short sequence
RT   reads: Sordaria macrospora, a model organism for fungal
RT   morphogenesis.";
RL   PLoS Genet. 6:E1000891-E1000891(2010).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCC13932.1}.
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DR   EMBL; CABT02000051; CCC13932.1; -; Genomic_DNA.
DR   RefSeq; XP_003347437.1; XM_003347389.1.
DR   STRING; 771870.XP_003347437.1; -.
DR   EnsemblFungi; CCC13932; CCC13932; SMAC_08441.
DR   GeneID; 10804866; -.
DR   KEGG; smp:SMAC_08441; -.
DR   EuPathDB; FungiDB:SMAC_08441; -.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   InParanoid; F7W9E1; -.
DR   KO; K02154; -.
DR   OrthoDB; EOG092C0YCY; -.
DR   Proteomes; UP000001881; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001881};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001881};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    422    447       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    467    487       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    549    567       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    587    606       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    645    668       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    788    813       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED      101    128       {ECO:0000256|SAM:Coils}.
FT   COILED      279    306       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   862 AA;  98119 MW;  D1E29DF9914198F3 CRC64;
     MAPKQDTPFR SADMSLVQLY ISNEIGREVC NALGELGLVQ FRDLNSELSA FQRAFTQDIR
     RLDNVERQLR YFHTQMEKAG IPLRKLDLDV DTLAPPTTTE IDELAEHAQS LEQRVSSLNE
     SYETLKKREV ELTESRWVLR EAGGFFDRAH GNVEEIRAST DNDDAPLLQD VEQHNTAADV
     ERSFSGMNIG FVAGVIGRDR VAAFERILWR TLRGNLYMNQ AEIPEPLVDP TTNEPVLKNV
     FVIFAHGKEI LAKIRRISES MGAEVYNVDE NSDLRRDQVH EVNARLNDVQ NVLRNTQQTL
     EAELSQISQS LSAWMILVSK EKAVYNTLNL FSYDRARRTL IAEGWCPTND LPLIRSTLQD
     VNNRAGLSVP SIINEIRTNK TPPTYLKTNK FTEAFQTIVN AYGTATYQEV NPAIPVIVTF
     PFLFAVMFGD FGHAVIMLCA ALAMIYWEKP LKKVTFELFA MVYYGRYIAL VMAIFSVYTG
     LIYNDVFSKS MTLFDSQWKW VVPDNYKNGD TVHAELREPN GYRYPFGLDW RWHGTENDLL
     FSNSYKMKMS IILGWAHMTY SLCFSYINAR HFKKPIDIWG NFVPGMIFFQ SIFGYLVLCI
     IYKWSVDWFG TGKQPPGLLN MLIYMFLQPG TLDGGIALYP GQATVQVILL LLAVIQVPIL
     LFLKPFYLRW ENNRARAKGY RGIGERSRVS ALDDDDDNGH TNGVHGDEGD DYEGAAMLTH
     DDHGDGEHEE FEFGEVMIHQ VIHTIEFCLN CVSHTASYLR LWALSLAHQQ LSAVLWSMTM
     AKALETTGIG GAIFLVVAFA MFFVLSVIIL IIMEGVSAML HSLRLAWVES FSKFAEFGGW
     PFAPFSFKQQ LEESEELREY MG
//
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