ID F7XFW2_SINMM Unreviewed; 593 AA.
AC F7XFW2;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Probabable glutathione-regulated potassium-efflux system protein {ECO:0000313|EMBL:AEH83438.1};
GN Name=kefB2 {ECO:0000313|EMBL:AEH83438.1};
GN OrderedLocusNames=SM11_pD0606 {ECO:0000313|EMBL:AEH83438.1};
OS Sinorhizobium meliloti (strain SM11).
OG Plasmid pSmeSM11d {ECO:0000313|EMBL:AEH83438.1,
OG ECO:0000313|Proteomes:UP000009045}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=707241 {ECO:0000313|EMBL:AEH83438.1, ECO:0000313|Proteomes:UP000009045};
RN [1] {ECO:0000313|EMBL:AEH83438.1, ECO:0000313|Proteomes:UP000009045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM11 {ECO:0000313|EMBL:AEH83438.1,
RC ECO:0000313|Proteomes:UP000009045};
RC PLASMID=pSmeSM11d {ECO:0000313|Proteomes:UP000009045};
RX PubMed=21396969; DOI=10.1016/j.jbiotec.2010.12.018;
RA Schneiker-Bekel S., Wibberg D., Bekel T., Blom J., Linke B., Neuweger H.,
RA Stiens M., Vorholter F.J., Weidner S., Goesmann A., Puhler A., Schluter A.;
RT "The complete genome sequence of the dominant Sinorhizobium meliloti field
RT isolate SM11 extends the S. meliloti pan-genome.";
RL J. Biotechnol. 155:20-33(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
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DR EMBL; CP001832; AEH83438.1; -; Genomic_DNA.
DR RefSeq; WP_010975839.1; NZ_JAJJBH010000002.1.
DR AlphaFoldDB; F7XFW2; -.
DR GeneID; 61600956; -.
DR KEGG; smx:SM11_pD0606; -.
DR PATRIC; fig|707241.3.peg.6294; -.
DR HOGENOM; CLU_005126_9_3_5; -.
DR Proteomes; UP000009045; Plasmid pSmeSM11d.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR004771; K/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR NCBIfam; TIGR00932; 2a37; 1.
DR PANTHER; PTHR46157; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR46157:SF4; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:AEH83438.1};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 408..530
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 593 AA; 62986 MW; 7C6DF5C14C95B7D5 CRC64;
MAAESHGIDL LPVIALLGAA VVAAPLFKRI GLGSVLGYLA AGIAIGPFGL RLLQEPSSIL
HVAELGVVMF LFIIGLEMRP SRLWGLRREI FGLGIVQVAL CALLLTGVGV LTGFPVAPSF
VAGAGFVLTS TAIVMQLLEE RREMAAPKGQ RIVSILLVED MAIVPLLALV AFLAPIVPGS
VAASGAIDWL SIAIGLVTIA GLVLAGRYLL NPLFGLIAGV EAREVMTAAA LMVVLGSAYV
MQLGGLSMAM GAFLAGVLLS ESTFRHQLEA DVEPFRGILL GLFFLAVGMS LDLGVIARNW
AMILFYVAAY MVVKAIVIYL VARLFRASNW EAIERAVFMA QGGEFAFVLY AAALGTGIIS
SEENAILTAI IIVSMMVTPL LIAALRLVER NIPLSTDGVE RPENLSGNVL IIGFGRVGQI
VSQVLLTRGH VISIIDTDVE MINTAREFDF KVYYGDGKRL DILHAAGAER ASAIVVCVDK
ADDATKIVEL IKAEFPLIPV LARASDRRHA LDLITAGADF HIRETFESSL VLGQKALEAL
GADLPEVAEI IEKVRQRDEK RLELELVGGL YAGRPLFSGK LEPVEAVPPG GSA
//
