ID F7XNB5_METZD Unreviewed; 890 AA.
AC F7XNB5;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=S-layer-related duplication domain protein {ECO:0000313|EMBL:AEH60076.1};
DE Flags: Precursor;
GN OrderedLocusNames=Mzhil_0197 {ECO:0000313|EMBL:AEH60076.1};
OS Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5)
OS (Methanohalophilus zhilinae).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosalsum.
OX NCBI_TaxID=679901 {ECO:0000313|EMBL:AEH60076.1, ECO:0000313|Proteomes:UP000006622};
RN [1] {ECO:0000313|Proteomes:UP000006622}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4017 / NBRC 107636 / OCM 62 / WeN5
RC {ECO:0000313|Proteomes:UP000006622};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA Ovchinnikova G., Daligault H., Detter J.C., Han C., Tapia R., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Spring S., Schueler E., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Methanosalsum zhilinae DSM 4017.";
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Secreted, cell wall, S-layer
CC {ECO:0000256|ARBA:ARBA00004237}.
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DR EMBL; CP002101; AEH60076.1; -; Genomic_DNA.
DR RefSeq; WP_013897515.1; NC_015676.1.
DR AlphaFoldDB; F7XNB5; -.
DR STRING; 679901.Mzhil_0197; -.
DR GeneID; 10821794; -.
DR KEGG; mzh:Mzhil_0197; -.
DR HOGENOM; CLU_014690_0_0_2; -.
DR Proteomes; UP000006622; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR CDD; cd00146; PKD; 2.
DR Gene3D; 2.60.40.4190; -; 2.
DR Gene3D; 2.60.98.40; -; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR026371; PGF_CTERM.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR InterPro; IPR006457; S_layer-rel_Mac.
DR NCBIfam; TIGR04126; PGF_CTERM; 1.
DR NCBIfam; TIGR01567; S_layer_rel_Mac; 2.
DR PANTHER; PTHR46730:SF1; PLAT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46730; POLYCYSTIN-1; 1.
DR Pfam; PF18204; PGF-CTERM; 1.
DR Pfam; PF18911; PKD_4; 2.
DR Pfam; PF07752; S-layer; 2.
DR SMART; SM00089; PKD; 2.
DR SUPFAM; SSF49299; PKD domain; 2.
DR PROSITE; PS50093; PKD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006622};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW S-layer {ECO:0000256|ARBA:ARBA00022601};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 868..885
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 728..777
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 805..863
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
SQ SEQUENCE 890 AA; 98763 MW; 43A1A96C1919AF8E CRC64;
MRKLAITLVA LMLMSLFAVG AATANNDDYV DELEIRGPVW DFTLTIEEVD APNNNTTLKT
FGDWRDLKID SDTFNTSANF NVSGELFSGT ELDAAQVENN VTNMTLVADA QNFAGFWYDI
DDGLSSETLT LYVNKTSGDR TLDDDDSDVL VYESNVQGVN ATFEFNGNVY QYPKIGFLAE
EYVPVESDGP LVEYDGQGVF GDVDKLSRLL MDTDDSWTLR VGETLDLEDG YAIEPQQIDV
EGDKVWLELT KDGEYVDDEI IDVSDSNDTT WFYDQTVLDE DDVVTLAISV DQVFQGTVDS
LVVIEGVWQI ADDGLEIETD DTFGNMAIES TSDAQIIMEL DSSITLRHDT TRNVMEDLKF
RMADDSDVLR FYLMQEVTEP GIHEVRGTVV DLEKDGGYYQ DAVSWTATGF DVPDLEEGVA
PEGFSFAGFY YDLDDNLHSE MLTIVEVERS LSDTSASDNP GIEYYSQPQI VESTFDFDGE
ERYYPKIGFL AEEYVPVSDE LLTTEEAELE GTSVDKLSKL LMDTDDSWTL RVGQTLDLED
GYAITPQQID VDGDKVWLEL TKDGEYVDDQ IIEVGDESTW FYDQTVLDEE DVTTLAIDVD
QVFQGTVDSL VVIEGAWQIA DDGMELETDD AFGKMVVESA DDNIVMTLDT SLTLRADSTQ
HLMGDIYFRV SDYSDFETDA RFYPFVERTV GEPVEPVEEE PVASFTANPT SGAAPLEVAF
TDQSEYAVDY SWDFGDGETS TEASPTHTYE EIGTYTVTLT VSNEIGEDTA ETTISVTEEE
ILPPVAAFDA QPLEGEVPLT VTFTDQSENA VAYEWDFGDG TTSTDATPTH TYEEAGEYTV
TLTVENELGE TDTAQTTITA TEPEPTPGFE AIFAIAGILA VAFLARRYRK
//
