ID F7XXF0_MOREP Unreviewed; 410 AA.
AC F7XXF0;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Putative peptidase, M23 family {ECO:0000313|EMBL:AEI74776.1};
GN OrderedLocusNames=MEPCIT_118 {ECO:0000313|EMBL:AEI74776.1};
OS Moranella endobia (strain PCIT).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Moranella.
OX NCBI_TaxID=903503 {ECO:0000313|EMBL:AEI74776.1, ECO:0000313|Proteomes:UP000000504};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PCIT;
RA McCutcheon J.P., von Dohlen C.D.;
RT "An interdependent metabolic patchwork in the nested three-way symbiosis of
RT mealybugs.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEI74776.1, ECO:0000313|Proteomes:UP000000504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCIT {ECO:0000313|EMBL:AEI74776.1,
RC ECO:0000313|Proteomes:UP000000504};
RX PubMed=21835622; DOI=10.1016/j.cub.2011.06.051;
RA McCutcheon J.P., von Dohlen C.D.;
RT "An interdependent metabolic patchwork in the nested symbiosis of
RT mealybugs.";
RL Curr. Biol. 21:1366-1372(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the peptidase M23B family.
CC {ECO:0000256|ARBA:ARBA00006646}.
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DR EMBL; CP002243; AEI74776.1; -; Genomic_DNA.
DR RefSeq; WP_013975527.1; NC_015735.1.
DR AlphaFoldDB; F7XXF0; -.
DR STRING; 903503.MEPCIT_118; -.
DR MEROPS; M23.011; -.
DR KEGG; men:MEPCIT_118; -.
DR eggNOG; COG0739; Bacteria.
DR HOGENOM; CLU_026846_0_2_6; -.
DR OrthoDB; 9805070at2; -.
DR Proteomes; UP000000504; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd12797; M23_peptidase; 1.
DR Gene3D; 3.10.450.350; -; 1.
DR Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR InterPro; IPR045834; Csd3_N2.
DR InterPro; IPR011055; Dup_hybrid_motif.
DR InterPro; IPR016047; Peptidase_M23.
DR PANTHER; PTHR21666:SF291; MUREIN DD-ENDOPEPTIDASE MEPM; 1.
DR PANTHER; PTHR21666; PEPTIDASE-RELATED; 1.
DR Pfam; PF19425; Csd3_N2; 1.
DR Pfam; PF01551; Peptidase_M23; 1.
DR SUPFAM; SSF51261; Duplicated hybrid motif; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000504};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 151..271
FT /note="Csd3-like second N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19425"
FT DOMAIN 283..377
FT /note="Peptidase M23"
FT /evidence="ECO:0000259|Pfam:PF01551"
SQ SEQUENCE 410 AA; 45719 MW; 305A3ABA69B530FD CRC64;
MQHITRFFSL AFNYFLSRSY HIMLGLLAIV TFTLTIAIWQ RQQYIYLPVV EPYDSDSHSN
LLEDEKLIDF TSTAIKLLGY TTPDHTEYLM KSELNNECME VVGGVNQHVI TSGDTINSVI
TQYGCGVTFH ATSTYDIVDG GVKEKKVNMT GEWRNTVLLT GQLNGSFINS ARLAGLTGSD
INAVIKALQW QLDFLKLRKG DQFSVLTTRN ESKNANSKLL GLRLRTGGKD YYAFRADDGK
FYNRDAAAGL ARGFMRFPTI KKFRVSSNFN PQRLNPITGR IAPHRGVDFA VPVGTPVLAV
GDGEVIVSKQ DGAAGNYVAI RHGRQYMTRY MHLKKLLVKP GQKVKRGACI ALSGNTGRST
GPHLHYEVWI NQQAVNPLTA KLPCTEVLIG HDRAEYLAQV KQILPQLQLN
//
