ID F8AG79_PYRYC Unreviewed; 444 AA.
AC F8AG79;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AEH23915.1};
GN OrderedLocusNames=PYCH_02160 {ECO:0000313|EMBL:AEH23915.1};
OS Pyrococcus yayanosii (strain CH1 / JCM 16557).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=529709 {ECO:0000313|EMBL:AEH23915.1, ECO:0000313|Proteomes:UP000008386};
RN [1] {ECO:0000313|EMBL:AEH23915.1, ECO:0000313|Proteomes:UP000008386}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH1 / JCM 16557 {ECO:0000313|Proteomes:UP000008386};
RX PubMed=21705594; DOI=10.1128/JB.05345-11;
RA Jun X., Lupeng L., Minjuan X., Oger P., Fengping W., Jebbar M., Xiang X.;
RT "Complete genome sequence of the obligate piezophilic hyperthermophilic
RT archaeon Pyrococcus yayanosii CH1.";
RL J. Bacteriol. 193:4297-4298(2011).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP002779; AEH23915.1; -; Genomic_DNA.
DR AlphaFoldDB; F8AG79; -.
DR STRING; 529709.PYCH_02160; -.
DR KEGG; pya:PYCH_02160; -.
DR eggNOG; arCOG01356; Archaea.
DR HOGENOM; CLU_042889_0_0_2; -.
DR OrthoDB; 2305at2157; -.
DR Proteomes; UP000008386; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR023980; CHP04013_B12-bd/rSAM.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR NCBIfam; TIGR04013; B12_SAM_MJ_1487; 1.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
FT DOMAIN 1..122
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 159..404
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 444 AA; 50746 MW; 94350D8422CB0DB7 CRC64;
MPEVALRLTR RNHNAFVHLL AALETQGYAL GDILVSKSLE EIIRAKPKIV LYSFYSQEVW
DVEREVKLLK ERTGAILVVG GYHATAMPRH TLRMGFDIAV IGEGEEVLYE LLTTLGRTGY
KVTKDLLNVK GLAFYLGGEF TFTGFAKVMD FSKFPPYPEA LRLISPMEIS RGCPFACYYC
QTPYMKGFRM RHRPIDQIVR YSRRMKDMRY ITPNAFAYGS PGAILRLDKL EALLKALQPL
RKEGRRLFYG TFPSEVRPEF VLPETLELLV QYTDTTRLAI GAQSGDDAML KAMHRLHKVE
HVVRAVELAL EYGLEPVVDF IVGLPNETEE SQRKSIELMK WIMRKGGKVR AHYFMPLPGT
PWARCKPSPL SDEMKKFLGK MAAEGKIEGS WGMQIEISRR LQRLIEEFYE EPFSYHGKVL
DICSDQKFIT QAEVGTTVNA PRKL
//
