ID F8CAD8_MYXFH Unreviewed; 382 AA.
AC F8CAD8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=S-(Hydroxymethyl)glutathione dehydrogenase {ECO:0000313|EMBL:AEI64595.1};
GN OrderedLocusNames=LILAB_13450 {ECO:0000313|EMBL:AEI64595.1};
OS Myxococcus fulvus (strain ATCC BAA-855 / HW-1).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=483219 {ECO:0000313|EMBL:AEI64595.1, ECO:0000313|Proteomes:UP000000488};
RN [1] {ECO:0000313|EMBL:AEI64595.1, ECO:0000313|Proteomes:UP000000488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-855 / HW-1 {ECO:0000313|Proteomes:UP000000488};
RX PubMed=21868801; DOI=10.1128/JB.05516-11;
RA Li Z.F., Li X., Liu H., Liu X., Han K., Wu Z.H., Hu W., Li F.F., Li Y.Z.;
RT "Genome sequence of the halotolerant marine bacterium Myxococcus fulvus HW-
RT 1.";
RL J. Bacteriol. 193:5015-5016(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP002830; AEI64595.1; -; Genomic_DNA.
DR AlphaFoldDB; F8CAD8; -.
DR STRING; 483219.LILAB_13450; -.
DR KEGG; mfu:LILAB_13450; -.
DR eggNOG; COG1063; Bacteria.
DR HOGENOM; CLU_026673_11_3_7; -.
DR Proteomes; UP000000488; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08283; FDH_like_1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 25..142
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 188..256
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 382 AA; 41243 MW; 0C0EDD70FF18336B CRC64;
MRALSYQGPY KVRVQDKPDP RIEHPQDVVL KVTKTAICGS DLHLLHGLIP DTRVGCTFGH
EFAGVVEELG PGVTNLKRGD RVVVPFNISC GACFYCEKGL TACCENSNPS SDIACGTFGY
SHTTGGYDGG QAEYVRVPFA NVGPMKIPED MDEEDVLFLS DIFPTGYMGA EMGGIQPGDT
VVVFGAGPVG LFAMKSAWLM GAGRVIAVDL QDYRLDFARK FAHVETLNFK DVDIVTAIKE
TTEGRGADVS IEAVGCEAEG SMLQRVLGLG LMAEAGATTA LNWCMHATRK GGVISVVGVY
GPPWNLVDIG TAMNKNQTLR LGQCNVKRYM PHLLDHIRKG RVDAKGLITH RFSLEDAPKA
YDLFSKKQDG CIKCVLSPHG HA
//
