ID F8CPS3_MYXFH Unreviewed; 981 AA.
AC F8CPS3;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=LILAB_05125 {ECO:0000313|EMBL:AEI62946.1};
OS Myxococcus fulvus (strain ATCC BAA-855 / HW-1).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=483219 {ECO:0000313|EMBL:AEI62946.1, ECO:0000313|Proteomes:UP000000488};
RN [1] {ECO:0000313|EMBL:AEI62946.1, ECO:0000313|Proteomes:UP000000488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-855 / HW-1 {ECO:0000313|Proteomes:UP000000488};
RX PubMed=21868801; DOI=10.1128/JB.05516-11;
RA Li Z.F., Li X., Liu H., Liu X., Han K., Wu Z.H., Hu W., Li F.F., Li Y.Z.;
RT "Genome sequence of the halotolerant marine bacterium Myxococcus fulvus HW-
RT 1.";
RL J. Bacteriol. 193:5015-5016(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP002830; AEI62946.1; -; Genomic_DNA.
DR AlphaFoldDB; F8CPS3; -.
DR STRING; 483219.LILAB_05125; -.
DR KEGG; mfu:LILAB_05125; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG0784; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_114_25_7; -.
DR Proteomes; UP000000488; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 4.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 3.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 4.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 4.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AEI62946.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:AEI62946.1}.
FT DOMAIN 220..273
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 357..575
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 608..721
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 733..847
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 861..976
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 264..353
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 657
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 782
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 909
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 981 AA; 107832 MW; 13761E554ADFD32A CRC64;
MASSQPPSES PADNASLLLV AGERECQRVE EALARAGVQV VTERATTAAA AEAALSRTWG
LVLCGSEVPD MGFAEVRALW SQYGKELPFV VLSRDWSEDT LEASVRAGAL DYITEDRFSR
LVPVVQRELR MTADRRRHTD TAVQLERTNY LMENIIDAIP FVLFVKDAQT RRLVVANKTF
ADAFRVTKQW LLGKLDHDYF PKEQADSFIA IDTEILETRQ MKSFEEVARA DGVDRIFSTR
KLPLLDEHGV ARYVMGVTED ITERKQHEEM LRASKAELEA ANKQLAASLE EIKRTRAVSA
RSLASYQQRA LQMEIIRQQN EDLDRLAQEL AVAKRNEEER AREAEAAARL KSEFLANFSH
EIRTPLNGII GYCDLLMREE GQRLTAHGRR DLNVVKTNAK TLLALINDIL DLSKIESGRV
EVVTEQVDVQ ELADECLATV KEYLKGKDVA LTTNIDPAAR MLRSDALKLR QIMLNLLSNA
AKFTEAGEVS LSLVPAGGEV VMTVEDTGVG IPSDQLPFIF EKFRQVDGST TRKVGGTGLG
LAIVRELSRV LGGNVSVTST LGRGTTFTVR LPTTLEAPDN GGGPHLERGV PVAEVAQHVG
AMAQPGSTVL VVDDDPLIQQ LVAGQLEPAG FKVVVAEDGI AALKRARELR PQAILLDIHL
PKLDGWSVLS QLKSEPSLAG IPVILISVEE QRARGFSLGA CEYLVKPVEP ERLVEVVQRS
LHQASGNSTS VGEVLVVDDD SATRELVSRN LRRAGFSTSE ARSGEDALLK ARVSPPALVV
LDLMMPNLDG FEVLRRLRAE KLQVPVVVLT GKTLSAEEEA LLRDGFAGFV KKGGHALEDV
IAQAKGLLLS QRAASAGKLA RILYVEDSAQ NRDIVRRYLN GHFEVIEAED GEHGLERAIR
DAPDLILMDL SLPRLDGWEV TRRLRALPAA ANVPVIAVTA HAGREYQDKA HEAGCTAYLT
KPLDRDQLLE MIRKHLGRTH V
//
