ID F8E7I8_FLESM Unreviewed; 392 AA.
AC F8E7I8;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:AEI14975.1};
GN OrderedLocusNames=Flexsi_1324 {ECO:0000313|EMBL:AEI14975.1};
OS Flexistipes sinusarabici (strain ATCC 49648 / DSM 4947 / MAS 10).
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Flexistipitaceae; Flexistipes.
OX NCBI_TaxID=717231 {ECO:0000313|EMBL:AEI14975.1, ECO:0000313|Proteomes:UP000006621};
RN [1] {ECO:0000313|EMBL:AEI14975.1, ECO:0000313|Proteomes:UP000006621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4947 / MAS 10 {ECO:0000313|Proteomes:UP000006621};
RX PubMed=22180813; DOI=10.4056/sigs.2235024;
RA Lapidus A., Chertkov O., Nolan M., Lucas S., Hammon N., Deshpande S.,
RA Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Pagani I., Ivanova N., Huntemann M., Mavromatis K., Mikhailova N., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Brambilla E.M., Rohde M.,
RA Abt B., Spring S., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Woyke T.;
RT "Genome sequence of the moderately thermophilic halophile Flexistipes
RT sinusarabici strain (MAS10).";
RL Stand. Genomic Sci. 5:86-96(2011).
RN [2] {ECO:0000313|Proteomes:UP000006621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4947 / MAS 10 {ECO:0000313|Proteomes:UP000006621};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Chertkov O.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Schroeder M.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Flexistipes sinusarabici DSM 4947.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002858; AEI14975.1; -; Genomic_DNA.
DR RefSeq; WP_013886459.1; NC_015672.1.
DR AlphaFoldDB; F8E7I8; -.
DR STRING; 717231.Flexsi_1324; -.
DR KEGG; fsi:Flexsi_1324; -.
DR eggNOG; COG0420; Bacteria.
DR HOGENOM; CLU_730993_0_0_0; -.
DR OrthoDB; 9773856at2; -.
DR Proteomes; UP000006621; Chromosome.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd00840; MPP_Mre11_N; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041796; Mre11_N.
DR PANTHER; PTHR30337; COMPONENT OF ATP-DEPENDENT DSDNA EXONUCLEASE; 1.
DR PANTHER; PTHR30337:SF0; NUCLEASE SBCCD SUBUNIT D; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000006621}.
FT DOMAIN 4..191
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
SQ SEQUENCE 392 AA; 45428 MW; A71F7CBF41312987 CRC64;
MPLSFIHTAD LHLGRGLDHF PDNSLEIYEH LLKTIETTAI KNNIDFILFA GDIFNSLDVD
ISIKKRFLDL IKNLGKHNIE IFYACGNHDY FQNKFYKPFL NERNFNIFPE HWQSFERNEA
VIHGYSFNKA AFKKKMLQDY TPATTDKTNI FCFHTNISEI SSRHENYAPS SIQEFEKFPP
NSFFGLGHIH QHNLIKEGKQ TILYPGSPIP TRIIETGEKG FYLVKQNSDE TFEKIFIKSG
TEIAEITLDI TGIEDFLEID DIIKENMDKY TDGKNLETTI PAYLSFKITL TGKLSPELKK
ELVKNISENY FEREMEGVYV MDNTRSMTSP ESIAEEKGLF EAMVKTYYNM EMDEVELDKN
IAELLEYSGD FNFDKAKDDA LLILYSMLKG DK
//
