ID F8GSB9_CUPNN Unreviewed; 559 AA.
AC F8GSB9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Na+/phosphate symporter NptA {ECO:0000313|EMBL:AEI79769.1};
GN Name=nptA {ECO:0000313|EMBL:AEI79769.1};
GN OrderedLocusNames=CNE_2c07980 {ECO:0000313|EMBL:AEI79769.1};
OS Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453
OS / N-1) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1042878 {ECO:0000313|EMBL:AEI79769.1, ECO:0000313|Proteomes:UP000006798};
RN [1] {ECO:0000313|EMBL:AEI79769.1, ECO:0000313|Proteomes:UP000006798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1
RC {ECO:0000313|Proteomes:UP000006798};
RX PubMed=21742890; DOI=10.1128/JB.05660-11;
RA Poehlein A., Kusian B., Friedrich B., Daniel R., Bowien B.;
RT "Complete genome sequence of the type strain Cupriavidus necator N-1.";
RL J. Bacteriol. 193:5017-5017(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002878; AEI79769.1; -; Genomic_DNA.
DR RefSeq; WP_013952480.1; NC_015723.1.
DR AlphaFoldDB; F8GSB9; -.
DR KEGG; cnc:CNE_2c07980; -.
DR HOGENOM; CLU_025623_2_1_4; -.
DR Proteomes; UP000006798; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR InterPro; IPR003841; Na/Pi_transpt.
DR InterPro; IPR004633; NaPi_cotrn-rel/YqeW-like.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; NF037997; Na_Pi_symport; 1.
DR NCBIfam; TIGR00704; NaPi_cotrn_rel; 1.
DR PANTHER; PTHR10010:SF39; PHOU DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR Pfam; PF02690; Na_Pi_cotrans; 2.
DR Pfam; PF01895; PhoU; 1.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 340..422
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT REGION 537..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 58936 MW; B4B23564A894C3E3 CRC64;
MQILLSLMSG VALLIWGAHV TRHGMLEVLG PRLRLVLAAG TASPARGFLA GLGVTALIQS
SSATALMTSA FVAGGLVSLP AALPIVLGAD VGTSLMARLL SVDISWLSPL LLVIGIALRL
SGKASLRGQT GEVIVGLGLI TLALQLIRLY AAPLLHAEIV RAVFTSLGHD ALLALVIGAL
VTLLAYSSLA AVLLTATLAM GGVIGPATAL PLVLGANLGS GLIACLANSG SSPAARRVSL
ANLIFRFVGI LAFLPMLDAM PWLLDRLGSS AGTMAIDFHM AFNLTLAATL VWFVNPVASL
CTRWLPDAHD DAAPSGARYL SQGDLRHPSV ALGNATREVV RIGNVIEEML NGMKLSIVGN
DRAVNARCRA LDDRIDALYS SVKMYLTDVD AGSLDGEDAT RWDEIMLVNI NLEYVGDIVE
RILVDLDQRK LSRNYCFSDE GSAELLELCD MLVANLRTRM SLFVANDRAA SALLIDCAGD
FQARAGRLTA RHIARVAQRR TASVETSALH LDTLRELSQM NALLCAAPAG MRGALPEDTS
FLPADNAGAP HAQERLLNP
//
