ID F8JC49_HYPSM Unreviewed; 395 AA.
AC F8JC49;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:CCB67672.1};
GN OrderedLocusNames=HYPMC_4463 {ECO:0000313|EMBL:CCB67672.1};
OS Hyphomicrobium sp. (strain MC1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Hyphomicrobium.
OX NCBI_TaxID=717785 {ECO:0000313|EMBL:CCB67672.1, ECO:0000313|Proteomes:UP000000494};
RN [1] {ECO:0000313|Proteomes:UP000000494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC1 {ECO:0000313|Proteomes:UP000000494};
RA Genoscope.;
RT "The complete genome of Hyphomicrobium sp. MC1.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FQ859181; CCB67672.1; -; Genomic_DNA.
DR AlphaFoldDB; F8JC49; -.
DR STRING; 717785.HYPMC_4463; -.
DR KEGG; hmc:HYPMC_4463; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_2_1_5; -.
DR Proteomes; UP000000494; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR000424; Primosome_PriB/ssb.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF24; HLYD FAMILY SECRETION PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS50935; SSB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00252};
KW Reference proteome {ECO:0000313|Proteomes:UP000000494}.
FT DOMAIN 76..294
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 368..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 395 AA; 42184 MW; 70156244EA240A43 CRC64;
MRVWKAALLG LIAIGGVAAY AYRAEIPKLL AEVESTGAPP HQGAFVMPVP VASVVKRPVS
IYLDYPARTE SINNITLQAR VSGYLQVQHV PDGSDVKEGT LLYTIDPRDY QAALDRAKAE
KQRDIAARDY AQSNLQRGTE LTKSGWLAKD TFDQRSSSLR QSEAAINIDD AAIRTAELNL
EYTQIRAPFS GRLGKNQAPI GTLISVAGAP LNTLVQLDPI YVTFNPSETD LDTIEKVRKS
GAIAAEVFVP GDSKPPHKGK ITFVDNAVDH LTGTLTARAT IANADYGLLP GQYVRIHVHA
GENPNALMVP QTAIGSSQLG KYVYVVGPKN IAEQKLVTLG PTEGDLVSVV GLEEKDLVIT
GNLQKIGPGS PVQPLTAPPP QANKAALQTG STTVN
//
