ID F8JSK5_STREN Unreviewed; 1056 AA.
AC F8JSK5; G8WUW7;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=SCATT_43600 {ECO:0000313|EMBL:AEW96731.1};
OS Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925
OS / NBRC 14057 / NRRL 8057) (Streptomyces cattleya).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptantibioticus.
OX NCBI_TaxID=1003195 {ECO:0000313|EMBL:AEW96731.1, ECO:0000313|Proteomes:UP000007842};
RN [1] {ECO:0000313|Proteomes:UP000007842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057
RC {ECO:0000313|Proteomes:UP000007842};
RA Ou H.-Y., Li P., Zhao C., O'Hagan D., Deng Z.;
RT "Complete genome sequence of Streptomyces cattleya strain DSM 46488.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003219; AEW96731.1; -; Genomic_DNA.
DR RefSeq; WP_014145083.1; NC_017586.1.
DR AlphaFoldDB; F8JSK5; -.
DR STRING; 1003195.SCATT_43600; -.
DR KEGG; scy:SCATT_43600; -.
DR PATRIC; fig|1003195.11.peg.5811; -.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_002554_0_0_11; -.
DR OrthoDB; 4652229at2; -.
DR Proteomes; UP000007842; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR013587; Nitrate/nitrite_sensing.
DR InterPro; IPR010910; Nitrate/nitrite_sensing_bac.
DR PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR PANTHER; PTHR44936:SF12; SENSOR PROTEIN CREC; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08376; NIT; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50906; NIT; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007842};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..371
FT /note="NIT"
FT /evidence="ECO:0000259|PROSITE:PS50906"
FT DOMAIN 589..696
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..1056
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..723
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 950..972
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1056
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1056 AA; 113356 MW; 9646A968B6709F60 CRC64;
MRNKRKRPEQ AEPARGNFTP PPGTGGGAQP SPGETGAPAR PSGGRFSPGN WRVRTRLNAI
LLIPVLVALV VGGFNVNSAV DRWSQADDAY RTAMLVRAAA TYSHALIDER DRTVVPLLKG
DDKNSAVLQA RAATDDAARQ FEDTVRQAPG TPDLQRRLAA FRQVQGRLPT LRQNAFTAKL
PGVQTEEGYV EVQHPLMEFA NDLGFGTSNI TSYGRTLYAI SLAKAAESLT RAIGTHILTE
GPVPAAELKT QQTALASYAY LENIALEEYK GGGTPEDLGR LQDAVAAAEA KGKQQLEQAR
GAQAAQGGTF TAPPDRATMV KLIASGASPA ALRAKGVTPQ SWWAATTLGF DAYRSIESHL
ADQAATDAQQ ISSDARTNAI VNAAAVLLGV LAAFVVAGLM ARAMSNRMRR LRSAAFEVAE
QRLPALVDQL SRTDPGRVDT RVTPIPITTG DEIGEVARAF DQVHREAVRL AAEQAMLRGN
VNAIFTNLSL RNQGLIQRQL ALITDLENNE ADPDQLENLF HLDHLATRMR RNGENLLVLA
GEEPGRRWNQ PVPLVDVVRA AASEVESYER IEISGVPETD IHGAAVTDLV HLLAELLENA
TSFSSPHTRV TVTATRLPDG RVMIEIHDKG IGLTAEDFAD INHKLADPPT VDAEVSKRMG
LFVVGRLADR HGIRVQLRPS GEQAGTTSLV MLPEPITHGG GGEEDEPGGD FQVSRRMPEH
SASDFHSGEF TAAELGFDER SFEVPDDARA LDPVGRSLLR EERRAALDRR RGDEDAPAPH
DEAAPADPSA FGGFPSPGQG FDQPQGFDQR TGFTPQPGYD QGLGQQAGFE QPGFEQAGFG
QGFEQRPEYP QQGWQGAEAE YQQTSWDPGY SQGTWANRVE PESPTGAPEG VGYDTPRNGS
SADSPDSATP GPDGPGETTA AGLPRRDRQR PWPPSASGAG ETSSLFDGAP RSDRTDDDEW
RSANDENWQR AEQVKLPKAG GVTSSGLPRR VPRANLVPGA AQQTPQGGPQ VSRAPEDVRG
RLSNLRRGVQ QGRTAGSDTP STPTDSQGLG PNHQER
//
