ID F8K4L6_STREN Unreviewed; 693 AA.
AC F8K4L6; G8WPJ3;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN OrderedLocusNames=SCATT_28050 {ECO:0000313|EMBL:AEW95176.1};
OS Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925
OS / NBRC 14057 / NRRL 8057) (Streptomyces cattleya).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptantibioticus.
OX NCBI_TaxID=1003195 {ECO:0000313|EMBL:AEW95176.1, ECO:0000313|Proteomes:UP000007842};
RN [1] {ECO:0000313|Proteomes:UP000007842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057
RC {ECO:0000313|Proteomes:UP000007842};
RA Ou H.-Y., Li P., Zhao C., O'Hagan D., Deng Z.;
RT "Complete genome sequence of Streptomyces cattleya strain DSM 46488.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
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DR EMBL; CP003219; AEW95176.1; -; Genomic_DNA.
DR RefSeq; WP_014143556.1; NC_017586.1.
DR AlphaFoldDB; F8K4L6; -.
DR STRING; 1003195.SCATT_28050; -.
DR KEGG; scy:SCATT_28050; -.
DR PATRIC; fig|1003195.11.peg.4303; -.
DR eggNOG; COG2518; Bacteria.
DR HOGENOM; CLU_397901_0_0_11; -.
DR OrthoDB; 4035289at2; -.
DR Proteomes; UP000007842; Chromosome.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027573; Methyltran_FxLD.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR023809; Thiopep_bacteriocin_synth_dom.
DR NCBIfam; TIGR04364; methyltran_FxLD; 1.
DR NCBIfam; TIGR03891; thiopep_ocin; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF14028; Lant_dehydr_C; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AEW95176.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007842};
KW Transferase {ECO:0000313|EMBL:AEW95176.1}.
FT DOMAIN 6..256
FT /note="Thiopeptide-type bacteriocin biosynthesis"
FT /evidence="ECO:0000259|Pfam:PF14028"
FT REGION 258..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 74313 MW; FEAC0DB2AF55C700 CRC64;
MPPERWQQHN ITFPDRDTAR RAITERLAPA LLAAEADGQL SGWWFMNKQP WPLRYVADRP
SPTMVALLDE LVADGIALSC TLAIYEAETE AFGGANAMTA AHALFHEDSR HLLNYPVCAG
HLGRRETAVL LMSSLMRAAN LDWFEQGDVW AKVAALRPGT DAPAPERSAT LISAMRTLMT
TEARSLCREG GPFDGHAEWI AAFERAGTTL AYLAAQGDLT RGLRAVIAHH VIFHANRAGL
PSEDQHALSH IAREAVMGSS ENTASAPAPG SAADSVSAVK TDTLTSAEAD AEQLRNALVD
QIKANGHART PAVEAALRAV PRHLFVPDAS LTDAYANAPV NIKYDSEGTS ISCASQPGIV
ALMLDQLDAQ PGERILELGA GTGYNAALLG HLVGPTGHVT TIDVDDDLVE GARAHLAAAG
VTNVEALTRD GALGHAEGAP YDRIVATVGA HGIPHAWLDQ LSPGGRLVTP QRLKGSVSRS
IIYEKHDGRW LSLGSEMNTF MPLRRGIADD DRRVVPLSAD GTVRLQAPSG QLIDADALAG
VLDQPRVEQW TEMTVRAGES PEWMELFVSC AVPSGLVRML FPQSAKGTVL TEDPYPSATA
AVEESTVTYL ARRPSEQKTP EGGKLWEFGV IGHGPGSDQL AAKVADAIRT WDREYRGREA
TFEALPLDGP AVEQRPGTFV LDTPLNRILV AWQ
//
