ID   F8K7Y6_STRPY            Unreviewed;       246 AA.
AC   F8K7Y6;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   03-MAY-2023, entry version 40.
DE   SubName: Full=Uncharacterized protein ORF19 {ECO:0000313|EMBL:CBX19865.1};
GN   Name=ORF19 {ECO:0000313|EMBL:CBX19865.1};
OS   Streptococcus pyogenes.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314 {ECO:0000313|EMBL:CBX19865.1};
RN   [1] {ECO:0000313|EMBL:CBX19865.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C1 {ECO:0000313|EMBL:CBX19865.1};
RA   Brenciani A., Tiberi E., Bacciaglia A., Petrelli D., Varaldo P.E.,
RA   Giovanetti E.;
RT   "Two distinct genetic elements are responsible for erm(TR)-mediated
RT   erythromycin resistance in tetracycline-susceptible and tetracycline-
RT   resistant strains of Streptococcus pyogenes.";
RL   Antimicrob. Agents Chemother. 55:6-12(2011).
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DR   EMBL; FR691054; CBX19865.1; -; Genomic_DNA.
DR   AlphaFoldDB; F8K7Y6; -.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 3.30.565.60; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001034; DeoR_HTH.
DR   InterPro; IPR025831; RecG_C.
DR   InterPro; IPR038475; RecG_C_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR30595:SF6; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR30595; GLPR-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR   Pfam; PF13749; HATPase_c_4; 1.
DR   Pfam; PF08220; HTH_DeoR; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          67..159
FT                   /note="ATP-dependent DNA helicase RecG C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13749"
FT   DOMAIN          198..234
FT                   /note="HTH deoR-type"
FT                   /evidence="ECO:0000259|Pfam:PF08220"
FT   REGION          168..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..183
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..199
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   246 AA;  28542 MW;  82EF5F8E8AABC619 CRC64;
     MDALDDIEFE GNIIYLLKAS LDFVKRNSKK MWKKGPVYRI EYPEYPERAV QEALVNALIH
     RDYSIIGSEV HVDIYDDRLE IYSPGGMYDG TFIQDINPLD VFSSRRNPII ADVFARMDLM
     ERRGSGLRKI IEAYEAEENY KEELKPEFKS TESSFTTILK NLNYDTQNVT QNDGQSEGQN
     EGENEGQNDG KKLKPKDRRN KIVKLMKENS NITTIELSHI LLVSVSTIER DLKISQMKNN
     RVYRQC
//