ID F8KPW5_HELBC Unreviewed; 376 AA.
AC F8KPW5;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=2-oxoglutarate oxidoreductase, alpha subunit {ECO:0000313|EMBL:CCB80859.1};
DE EC=1.2.7.3 {ECO:0000313|EMBL:CCB80859.1};
GN OrderedLocusNames=HBZC1_18730 {ECO:0000313|EMBL:CCB80859.1};
OS Helicobacter bizzozeronii (strain CIII-1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1002804 {ECO:0000313|EMBL:CCB80859.1, ECO:0000313|Proteomes:UP000008387};
RN [1] {ECO:0000313|EMBL:CCB80859.1, ECO:0000313|Proteomes:UP000008387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIII-1 {ECO:0000313|EMBL:CCB80859.1,
RC ECO:0000313|Proteomes:UP000008387};
RX PubMed=21705603; DOI=10.1128/JB.05439-11;
RA Schott T., Rossi M., Hanninen M.L.;
RT "Genome sequence of Helicobacter bizzozeronii strain CIII-1, an isolate
RT from human gastric mucosa.";
RL J. Bacteriol. 193:4565-4566(2011).
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DR EMBL; FR871757; CCB80859.1; -; Genomic_DNA.
DR RefSeq; WP_013891230.1; NC_015674.1.
DR AlphaFoldDB; F8KPW5; -.
DR STRING; 1002804.HBZC1_18730; -.
DR KEGG; hbi:HBZC1_18730; -.
DR eggNOG; COG0674; Bacteria.
DR HOGENOM; CLU_017038_0_0_7; -.
DR Proteomes; UP000008387; Chromosome.
DR GO; GO:0047553; F:2-oxoglutarate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR32154:SF14; 2-OXOGLUTARATE SYNTHASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:CCB80859.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008387}.
FT DOMAIN 15..247
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 275..369
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 376 AA; 41620 MW; 328BEBF38666B0E5 CRC64;
MRELISDGNE LVAQAAIDAG CRFFGGYPIT PSSDIMHAMS LLLPAHEGHF MQMEDEIGGI
CVALGASMSG VKSMTASSGP GISLKVEQIG YSYMTETPLV IVDVMRSGPS TGMPTRVAQG
DISFLKHPIH GDFQSVTLAP GNLQEAYTET IRAFNLAEKL MTPVFLVLDE TIGHMYGRVE
LPDLEAVQKS IINRRVFKGD PKDYKPYGVP LDESAILNPF FTGYRYHVTG LHHDAIGFPT
EDAKVGGELM DRLFNKINSQ AESVNLDEEI DIEGADLLVI GYGSSALCVK EALRDLKTQN
YPKKVGFFRP LTLWPSPRKR LQELGKQFEK ILVVELNKGQ YIHEIEHVMH RKVEGLLQAN
GRPFSPKQIM AKIKEL
//
