ID   F8L564_SIMNZ            Unreviewed;       748 AA.
AC   F8L564;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=DNA methylase N-4/N-6 domain-containing protein {ECO:0000259|Pfam:PF01555};
GN   OrderedLocusNames=SNE_A00670 {ECO:0000313|EMBL:CCB87945.1};
OS   Simkania negevensis (strain ATCC VR-1471 / Z).
OC   Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Simkaniaceae;
OC   Simkania.
OX   NCBI_TaxID=331113 {ECO:0000313|EMBL:CCB87945.1, ECO:0000313|Proteomes:UP000000496};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Z;
RA   Collingro A., Tischler P., Weinmaier T., Penz T., Heinz E., Brunham R.C.,
RA   Read T.D., Bavoil P.M., Sachse K., Kahane S., Friedman M.G., Rattei T.,
RA   Myers G.S.A., Horn M.;
RT   "Unity in variety -- the pan-genome of the Chlamydiae.";
RL   Mol. Biol. Evol. 0:0-0(2011).
RN   [2] {ECO:0000313|EMBL:CCB87945.1, ECO:0000313|Proteomes:UP000000496}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1471 / Z {ECO:0000313|Proteomes:UP000000496};
RX   PubMed=21690563; DOI=10.1093/molbev/msr161;
RA   Collingro A., Tischler P., Weinmaier T., Penz T., Heinz E., Brunham R.C.,
RA   Read T.D., Bavoil P.M., Sachse K., Kahane S., Friedman M.G., Rattei T.,
RA   Myers G.S., Horn M.;
RT   "Unity in variety--the pan-genome of the Chlamydiae.";
RL   Mol. Biol. Evol. 28:3253-3270(2011).
CC   -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00006594}.
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DR   EMBL; FR872582; CCB87945.1; -; Genomic_DNA.
DR   AlphaFoldDB; F8L564; -.
DR   STRING; 331113.SNE_A00670; -.
DR   REBASE; 37550; M.SneZORF670P.
DR   KEGG; sng:SNE_A00670; -.
DR   eggNOG; COG1743; Bacteria.
DR   HOGENOM; CLU_007795_1_0_0; -.
DR   Proteomes; UP000000496; Chromosome gsn.131.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR002941; DNA_methylase_N4/N6.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR001091; RM_Methyltransferase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF01555; N6_N4_Mtase; 1.
DR   PRINTS; PR00508; S21N4MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000496};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          118..151
FT                   /note="DNA methylase N-4/N-6"
FT                   /evidence="ECO:0000259|Pfam:PF01555"
SQ   SEQUENCE   748 AA;  84787 MW;  2BB4E1D520D84DFD CRC64;
     MIPPHLVNCP KAIFSSEQSV AYPSKLEMAD LKLSGICSPD NPWETISSSI ENDFPFVEIS
     EIAEIESWRK EVYRPIYHLH KWWAQRLGSV FRSIILGSSL PNKTSVLHHF YSKTDLGGLV
     VFDPFMGSGT TIGEAIKLGC TVIGRDINPV AYNGVRAAFS NVNTEDVEST FNILEENVGR
     KVRSLYQLSD GSEVLYYFWV KHVNCPDCKA PVDLFNNYIF SKHAYSSRFP QSKCLCPKCG
     EVFSARFDST AEQCPSCSFA FDPQIGPTEK AKATCSTCHC QFAIASIVKE SGKPPEHRMY
     AKIVLTPENK KEYRKITSED LLKFSQINDL LCQEPPLINK TELKPGKNTT QAMNYCYTQW
     EQFFNPRQLL ALSWLGKEIQ KIENQNLRLI FSILFSGTLE FNNMFCSFKG EGTGAVRHMF
     SHHILKPERH PIEANVWGTS KSSGAFSSLF KSRLLRCLKY RENPFEIEVS KNKKVGTKNF
     KCNKPIGRDL NFVNRSDELR PYSVYLSCGD SSKTDLHDQS VDLVVTDPPF FDNVHYSELA
     DFFYAWQHPL LGDMTATSDT TRHPNEVQDA DSQKFSEKLA AVFSECHRVL KDTGMLVFTY
     HHSKEEGWSA VSHAVASAGF NFVSAQPVKA EMSIAVPKQQ AKDPIDLDII LVCRKASQDS
     RSRFSLQQAV ISASERTDSQ IERFWESDRK LSRNDLRIII LSNLLVQLSS GRMSKELQLE
     FDRAALLIND KIDKYLEKQA LCLQKSKA
//