ID F8N3W9_NEUT8 Unreviewed; 672 AA.
AC F8N3W9;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=DNA/RNA polymerase {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEUTE1DRAFT_149518 {ECO:0000313|EMBL:EGO51819.1};
OS Neurospora tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510951 {ECO:0000313|EMBL:EGO51819.1};
RN [1] {ECO:0000313|EMBL:EGO51819.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FGSC 2508 {ECO:0000313|EMBL:EGO51819.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Ellison C.E., Stajich J.E., Jacobson D.J., Lindquist E., Lapidus A.,
RA Foster B., Aerts A., Riley R., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GL891382; EGO51819.1; -; Genomic_DNA.
DR RefSeq; XP_009855461.1; XM_009857159.1.
DR AlphaFoldDB; F8N3W9; -.
DR GeneID; 20827119; -.
DR KEGG; nte:NEUTE1DRAFT149518; -.
DR VEuPathDB; FungiDB:NEUTE1DRAFT_149518; -.
DR HOGENOM; CLU_012348_7_1_1; -.
DR OrthoDB; 118267at2759; -.
DR Proteomes; UP000008065; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR041298; UBZ3.
DR InterPro; IPR001126; UmuC.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45873; DNA POLYMERASE ETA; 1.
DR PANTHER; PTHR45873:SF1; DNA POLYMERASE ETA; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR Pfam; PF18439; zf_UBZ; 1.
DR PIRSF; PIRSF036603; DPol_eta; 2.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
DR PROSITE; PS51907; ZF_UBZ3; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 46..308
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT DOMAIN 590..625
FT /note="UBZ3-type"
FT /evidence="ECO:0000259|PROSITE:PS51907"
FT REGION 562..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..672
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 672 AA; 74426 MW; 3BE11B3A992087EA CRC64;
MSSPPHMQSF RDLSPAGAPG MKRSRFTYRH IQQLAASSTS CPLRVIAHLD LDCFYAQVEM
VRLGIPDDKP VAVQQWQGLI AVNYPARSFG IGRHCNVSEA KKLCPDLIHQ HVATWREGDA
KWDYHPDAAA NMATHKVSLD PYRLESRKIL AIIKEELPPH LQKVEKASID ELFMDLSAQV
HTILIERFPE LANPPPYDDP TEMLPMPSIT ALDWQADALV DLPDENAELE DPDWDDVAIL
IGSEIVRKVR IAIKDKLGYT CSAGVACNKL LSKLGSAYRK PNQQTVLRNR SIQHFLSDFK
FTKMRNLGGK LGEQISQMFH TDTVKDLLSA SVEQLKSKLG DDTGVWVYNT VRGIDTSEVN
PRVHIKSMLS AKSFRPSITS FEQAVRWLRI FAADIFSRLV EEGVLENKRR PKTINLHHRH
GTQTRSRQGP IPQGRKLDEE SLLELARNLL SQIVSEGQVW PCSNLGLSVG GFEDGVTGNM
GIGAFLLKGE EAQASKMASG TATVDSEIEI RPAEKRRRLD NGGIERFFAK RELSHGANSG
LGSDDTAISG QSGQRLGTLK EEVMSGEPAG SEGVGKGDEV YNGKSESEPG PIITLTCSRC
NASLDSPEEL QSHQDWHFAK ELQEQERVSQ TFVNQPSASS SRAGNPKSTS TTPKRQGRPK
KVERGQSKLK FG
//
