ID F8QFR7_SERL3 Unreviewed; 629 AA.
AC F8QFR7;
DT 21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT 21-SEP-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=PIN domain-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SERLA73DRAFT_190513 {ECO:0000313|EMBL:EGN92901.1};
OS Serpula lacrymans var. lacrymans (strain S7.3) (Dry rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Coniophorineae; Serpulaceae; Serpula.
OX NCBI_TaxID=936435 {ECO:0000313|Proteomes:UP000008063};
RN [1] {ECO:0000313|Proteomes:UP000008063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain S7.3 {ECO:0000313|Proteomes:UP000008063};
RX PubMed=21764756; DOI=10.1126/science.1205411;
RA Eastwood D.C., Floudas D., Binder M., Majcherczyk A., Schneider P.,
RA Aerts A., Asiegbu F.O., Baker S.E., Barry K., Bendiksby M., Blumentritt M.,
RA Coutinho P.M., Cullen D., de Vries R.P., Gathman A., Goodell B.,
RA Henrissat B., Ihrmark K., Kauserud H., Kohler A., LaButti K., Lapidus A.,
RA Lavin J.L., Lee Y.-H., Lindquist E., Lilly W., Lucas S., Morin E.,
RA Murat C., Oguiza J.A., Park J., Pisabarro A.G., Riley R., Rosling A.,
RA Salamov A., Schmidt O., Schmutz J., Skrede I., Stenlid J., Wiebenga A.,
RA Xie X., Kuees U., Hibbett D.S., Hoffmeister D., Hoegberg N., Martin F.,
RA Grigoriev I.V., Watkinson S.C.;
RT "The plant cell wall-decomposing machinery underlies the functional
RT diversity of forest fungi.";
RL Science 333:762-765(2011).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; GL945497; EGN92901.1; -; Genomic_DNA.
DR AlphaFoldDB; F8QFR7; -.
DR STRING; 936435.F8QFR7; -.
DR eggNOG; KOG2519; Eukaryota.
DR HOGENOM; CLU_021984_0_0_1; -.
DR InParanoid; F8QFR7; -.
DR OMA; PFLQKTC; -.
DR OrthoDB; 1430882at2759; -.
DR Proteomes; UP000008063; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11081:SF74; XPGN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000008063}.
FT DOMAIN 1..100
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 435..505
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 140..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 70423 MW; E307B42A074C9439 CRC64;
MGVLGLTPFL QKTCPEVIRK LPDRLRSLRG KTIVIDGTLI TQRFHFAPIP HQHRHVLGWH
RMVTELKECG VKAICVFDGK ERNAAKAREV ERRREVRKLD AARGSIEVER LSRLRKLARL
LLQCRSLEAH DRDRVTQTLR NISSSRYPSA QSANGIWQAP PAPEQLSTGQ ETPWPASKEP
PSGKGLGATS PLPVNIELPA PHHGSNWEDN SSSSFDLVDI SQSDIRDILL SRIGQVVSVP
HEVQEPYDLS YQDCSQMSEI AERKVSEEHP DLFRRLDKSS SVFISEEPNN AMSQFNSIAG
PSYDMSSTSK IETIVAKDIL CALSSLYIDY RQSIARVTSL PSPLYSQQAS ESTEDAAEAR
LEYAMSKSQL QLTLDEGKVW DELVDPPGLF EDVTGAAEIS LALLAEKSSI ISESYERRTH
PPSLQTYQEC REIIRAMGIP CIESTGPFEA EALASSLVIN GFADYVASED TDVLVYEAPL
IRNIANREGP LIVVSGSDVR SVLQLERSSY IDFALLLGTD FSQRIKNVGP QRALKFIREY
GSIERVLEQE IKYPPRMPLP IYLRQVELAR TVFQTLPPVP NPDLLQTAAG DTTQVFEILQ
RYNLQRHITN HWDHQTTLAG NYFGDNPTA
//
