ID   F8TUB3_9GAMM            Unreviewed;       438 AA.
AC   F8TUB3;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=RND family efflux transporter MFP subunit {ECO:0000313|EMBL:AEH59025.1};
OS   Lysobacter sp. ATCC 53042.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Lysobacter.
OX   NCBI_TaxID=324869 {ECO:0000313|EMBL:AEH59025.1};
RN   [1] {ECO:0000313|EMBL:AEH59025.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 53042 {ECO:0000313|EMBL:AEH59025.1};
RX   PubMed=21609846; DOI=10.1016/j.chembiol.2011.02.012;
RA   Hou J., Robbel L., Marahiel M.A.;
RT   "Identification and characterization of the lysobactin biosynthetic gene
RT   cluster reveals mechanistic insights into an unusual termination module
RT   architecture.";
RL   Chem. Biol. 18:655-664(2011).
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
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DR   EMBL; JF412274; AEH59025.1; -; Genomic_DNA.
DR   AlphaFoldDB; F8TUB3; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   InterPro; IPR006143; RND_pump_MFP.
DR   NCBIfam; TIGR01730; RND_mfp; 1.
DR   PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   PANTHER; PTHR30469:SF12; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          88..136
FT                   /note="Membrane fusion protein biotin-lipoyl like"
FT                   /evidence="ECO:0000259|Pfam:PF13533"
FT   REGION          395..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  45189 MW;  07DC38BEF1547A33 CRC64;
     MRSTPNASPA PPPPAAERGS WLRRHRGLLL TLLGVAALLA LAWWLVHGRA ANERGNRRPT
     ATVGIATAAS GTIPITLEAL GTVTPLATAT VRAQVAGNIV DIAFKEGQQV AKGEVLLRID
     PRPFQLALDQ ARGALARDQA QLQVAQLTLK RYAPLAHDQT IAQQDYDTQA ATVRQLTGVV
     ATDQAAVGTA QLNLDYTQVR APIAGRVGLR VVDLGNYVTP GDAAGVAVIS AVTPIDVEFT
     APQDELPRIQ ARLAHGDPPA VTALDRTRTQ VLGQGRFLTL DNVIDPGTGT VKAKARFDNA
     DARLFPSQFV NVRVLLDTLN DAITVPAAAL RTGPNGDFVY VVGADRKAQL RKVVRGPAAG
     DTVSVTQGLK LGEQVVISGG DQLNDGAAVR LPGDAGGAGG AGGASGEGKA AAGAGGHHRG
     GRAQGATDGG DGQRSRAP
//