ID F9D2I2_PREDD Unreviewed; 708 AA.
AC F9D2I2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Subtilase family domain protein {ECO:0000313|EMBL:EGQ15645.1};
DE SubName: Full=Subtilisin-like serine protease {ECO:0000313|EMBL:AGB28473.1};
GN OrderedLocusNames=Prede_1145 {ECO:0000313|EMBL:AGB28473.1};
GN ORFNames=HMPREF9136_1010 {ECO:0000313|EMBL:EGQ15645.1};
OS Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043
OS / ES 2772) (Mitsuokella dentalis).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=908937 {ECO:0000313|EMBL:EGQ15645.1, ECO:0000313|Proteomes:UP000007820};
RN [1] {ECO:0000313|EMBL:EGQ15645.1, ECO:0000313|Proteomes:UP000007820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:EGQ15645.1,
RC ECO:0000313|Proteomes:UP000007820};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000010862}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772
RC {ECO:0000313|Proteomes:UP000010862};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AGB28473.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:AGB28473.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CP003368; AGB28473.1; -; Genomic_DNA.
DR EMBL; AFPW01000013; EGQ15645.1; -; Genomic_DNA.
DR RefSeq; WP_005844958.1; NZ_GL982488.1.
DR AlphaFoldDB; F9D2I2; -.
DR STRING; 908937.Prede_1145; -.
DR KEGG; pdt:Prede_1145; -.
DR PATRIC; fig|908937.9.peg.1191; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_020737_0_0_10; -.
DR OrthoDB; 1489355at2; -.
DR Proteomes; UP000007820; Unassembled WGS sequence.
DR Proteomes; UP000010862; Chromosome 1.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF00082; Peptidase_S8; 2.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000010862};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 152..353
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 485..646
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 161
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 223
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 596
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 708 AA; 76506 MW; BDBB4FB26439F01D CRC64;
MKKPSCLFAA AWFALLMTGL LVLLSPMEAA AQRAVLSKMS PLVREAWLHA RQERPHFRKG
LPARPAVLTA FVKTADAGSQ VLETAGCRVL ARYGTLAIAE IPLNRLDTLA RNGHVLRIEA
GRRATALMDT TALIVQAPAV YEGLNLPQGY TGRGVLVGVQ DIGFDLTHPN FYSSDFSTYR
VRALWDQLST DTLGSALPVG RDYVGRAELL SLGHPRDGLI QTHGTHTAGI AAGSGAEGPG
VNSPYRGIAY ESDLCLVSNA VSEDASLIDP ADYYKYTFAL DALGFKYIFD QADRMGKPCV
INFSEGSQQD FHGYDRLYYE MLDSLCGPGR IIVSSAGNAG QGINYVEKPA GTASAGVFCT
SGQARVYATA KADGDYTLRL SFYRDSLPAL VRDYKLSAVL ARPDSMLRDT LRLDTARYVV
TAMAYPSAYD ASETVCDWAI STSGQPFRNG APASLQLVGR EARVELFPVT GSFYHSAIDP
TLCSGDNTHS VYSPASAPRV ICVGATAYRT QFVNYLGNLM VYDNGTDGRR TPYSAVGPTW
DGRLKPDVMA PGQNVVSSYS SFYLEHNPTA RDLTSDVRHF TYGGRTYAWN SNGGTSMASP
VVAGVIALWL QADPKLTPED CLEVMASTCR HPDPTLHYPN QLYGHGEIDA YAGLQAVLVR
QAADVAVVSP RPAASAIYSL DGRYAGTDVS RLQRGIYVRA GQKIVVRH
//
