ID F9D4X2_PREDD Unreviewed; 797 AA.
AC F9D4X2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:AGB29020.1, ECO:0000313|EMBL:EGQ13393.1};
DE EC=3.2.1.23 {ECO:0000313|EMBL:EGQ13393.1};
GN Name=bga {ECO:0000313|EMBL:EGQ13393.1};
GN OrderedLocusNames=Prede_1721 {ECO:0000313|EMBL:AGB29020.1};
GN ORFNames=HMPREF9136_1900 {ECO:0000313|EMBL:EGQ13393.1};
OS Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043
OS / ES 2772) (Mitsuokella dentalis).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=908937 {ECO:0000313|EMBL:EGQ13393.1, ECO:0000313|Proteomes:UP000007820};
RN [1] {ECO:0000313|EMBL:EGQ13393.1, ECO:0000313|Proteomes:UP000007820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:EGQ13393.1,
RC ECO:0000313|Proteomes:UP000007820};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000010862}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772
RC {ECO:0000313|Proteomes:UP000010862};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 2 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AGB29020.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3688 {ECO:0000313|EMBL:AGB29020.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 2 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CP003369; AGB29020.1; -; Genomic_DNA.
DR EMBL; AFPW01000028; EGQ13393.1; -; Genomic_DNA.
DR RefSeq; WP_005846510.1; NZ_GL982489.1.
DR AlphaFoldDB; F9D4X2; -.
DR STRING; 908937.Prede_1721; -.
DR KEGG; pdt:Prede_1721; -.
DR PATRIC; fig|908937.9.peg.1820; -.
DR eggNOG; COG3250; Bacteria.
DR HOGENOM; CLU_006501_0_1_10; -.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000007820; Unassembled WGS sequence.
DR Proteomes; UP000010862; Chromosome 2.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR040605; Glyco_hydro2_dom5.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF18565; Glyco_hydro2_C5; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:EGQ13393.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGQ13393.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010862};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..797
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010496686"
FT DOMAIN 26..187
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 201..301
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 311..464
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 614..677
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
FT DOMAIN 690..791
FT /note="Glycoside hydrolase family 2"
FT /evidence="ECO:0000259|Pfam:PF18565"
SQ SEQUENCE 797 AA; 90870 MW; 8CBE117C7C0EA77E CRC64;
MQKPICTLLT LFLLAAPAMG QRTVEYLNDG WKFHWGQADP QHLNTEGWRT VDVPHDFQIE
QPWVAPSADE RENNSDGASN FKSRLSARAF KEMGEGWYVK TITPDAGWQG RRVLIDFEGI
MYVGDVYLNG ERVGGTDYGY VGFEIDLSRK LRYGQPNTIA VRASTGSPTD SRWYTGGGLF
RNVHLVTTDA QLYFARHPLY VTTTDNREVH VQVEVANLTK YNSVNLQLEL IDNTGRTVYA
KRQDMPYMRR YKTNELRWEP VVVSDAHLWN IDDPYRYTAR VTLYNHEGRA VDCVSTRFGI
RNFEIGPDFG LKLNGRKLLL KGIANHHTLG ALGAAAYPRA MEKRLKLLKD FGFNHVRTSH
NPYSESFLNL CDSLGFVVVD ELYDKWLQQY TGGRTPWMQQ WPYQLPEWIK RDRNHPCVAL
WSLGNELQTY ANLPFDDGGV TPYRMLKAVL QRYDDTRKVT VAMHPRGRNL QTDSLPCDLA
LQTDVQAYNY RYMYFPGDGR KFPWMTFYQS EANLSMMGPN FFGMDLDKVI GLAYWGMIDY
LGESMGWPRK GWTDGVFDIS LQPKPMAWLL RSMFKPEEPV CHIGIVDSKA RQTEWNGIVF
SNDGMSDHWN RIPGQQLTVK VFTNAHRVEL VENGHKIAEQ ANTADPQKRN QLQFDQVTYQ
PGWLEAVAYD EKGKRVASHR IETAGEMKRL KAEPDAEVWH ADGQDLQHVR ITALDSRGRR
AVSAQQRLTF SVTGDARIVA VDNGNNASDE LHAVAERSLC NGSALVILRA GKKAGKVVLT
IRDDKGKSQK LVLNTVK
//
