ID F9DT98_9BACL Unreviewed; 315 AA.
AC F9DT98;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Acetoin dehydrogenase E1 component subunit alpha {ECO:0000313|EMBL:EGQ25944.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:EGQ25944.1};
GN Name=acoA {ECO:0000313|EMBL:EGQ25944.1};
GN ORFNames=HMPREF9372_2029 {ECO:0000313|EMBL:EGQ25944.1};
OS Sporosarcina newyorkensis 2681.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Sporosarcina.
OX NCBI_TaxID=1027292 {ECO:0000313|EMBL:EGQ25944.1, ECO:0000313|Proteomes:UP000005316};
RN [1] {ECO:0000313|EMBL:EGQ25944.1, ECO:0000313|Proteomes:UP000005316}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2681 {ECO:0000313|EMBL:EGQ25944.1,
RC ECO:0000313|Proteomes:UP000005316};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGQ25944.1}.
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DR EMBL; AFPZ01000065; EGQ25944.1; -; Genomic_DNA.
DR RefSeq; WP_009498685.1; NZ_GL982999.1.
DR AlphaFoldDB; F9DT98; -.
DR STRING; 759851.SAMN04244570_3613; -.
DR eggNOG; COG1071; Bacteria.
DR HOGENOM; CLU_029393_5_0_9; -.
DR OrthoDB; 9766715at2; -.
DR Proteomes; UP000005316; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EGQ25944.1}.
FT DOMAIN 12..304
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
FT REGION 244..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 34140 MW; 390B60911C106612 CRC64;
MDQQTALWIY QKMNEIRFFE EEVHHIFGKG LIPGFVHLYA GEEAVATGVM ALLDDEDYIT
STHRGHGHAI AKGCDIKGMM AEIMGKKDGL GGGKGGSMHV ADIDRGMLGA NGIVGGGFGL
AAGAALTIKT LGQSHVAVCF FGDGASNEGT FHEGLNLASI LDLPVIFVCE NNQFGEGTPF
RYASASETVA ERAPAYNMPG VRVDGMDVEA VYEATEKAIK RAKAGEGPTL IECDTYRHFG
HFEGDEQKYK TDQDPNRDRD PITEFREKAT KNKWMTSEQA DEIESNAKKT VEDAVAFAEA
SPLPDESTLY TDIFA
//
